Microglia: active sensor and versatile effector cells in the normal and pathologic brain
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Cites background from "Microglia: active sensor and versat..."
...…are the resident CNS immune cells which have long been recognized as rapid responders to injury and disease, play- ing a role in a broad range of processes such as tissue inflammation and clearance of cellular debris (Hanisch and Kettenmann, 2007; Kreutzberg, 1996; Ransohoff and Perry, 2009)....
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...Particularly during CNS disease, microglia are known scavengers that phagocytose cellular debris (Hanisch and Kettenmann, 2007; Napoli and Neumann, 2009; Ransohoff and Perry, 2009)....
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...Microglia are the resident CNS immune cells which have long been recognized as rapid responders to injury and disease, playing a role in a broad range of processes such as tissue inflammation and clearance of cellular debris (Hanisch and Kettenmann, 2007; Kreutzberg, 1996; Ransohoff and Perry, 2009)....
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Cites background from "Microglia: active sensor and versat..."
...This concept should replace the notion that microglia proceed from resting to activated (76)....
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References
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"Microglia: active sensor and versat..." refers background in this paper
...Middle, upon detection of minute homeostatic disturbances, for example tiny vascular or tissue damage, microglia can rapidly respond with a directed reorganization of processes and a change in the activity profile (4)....
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