Mindfulness-based therapy: A comprehensive meta-analysis

doi:10.1016/J.CPR.2013.05.005

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Mindfulness-based therapy: A comprehensive meta-analysis

Journal Article•DOI•

Mindfulness-based therapy: A comprehensive meta-analysis

Bassam Khoury¹, Tania Lecomte¹, Guillaume Fortin¹, Marjolaine Masse¹, Phillip Therien¹, Vanessa Bouchard², Marie-Andrée Chapleau¹, Karine Paquin¹, Stefan G. Hofmann³ - Show less +5 more•Institutions (3)

Université de Montréal¹, Laval University², Boston University³

01 Aug 2013-Clinical Psychology Review (Clin Psychol Rev)-Vol. 33, Iss: 6, pp 763-771

TL;DR: Mindfulness-based therapy is an effective treatment for a variety of psychological problems, and is especially effective for reducing anxiety, depression, and stress.

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About: This article is published in Clinical Psychology Review.The article was published on 2013-08-01. It has received 1491 citations till now.

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Journal Article•DOI•

Meta-analytic procedures for social research

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Gwenn W. Gröndal

01 Jun 1993-Evaluation Practice

1,174 citations

Journal Article•DOI•

Mindfulness-based stress reduction for healthy individuals: A meta-analysis.

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Bassam Khoury¹, Bassam Khoury², Manish Sharma³, Sarah E. Rush⁴, Claude Fournier - Show less +1 more•Institutions (4)

McGill University¹, Harvard University², RMIT University³, University of Alabama⁴

01 Jun 2015-Journal of Psychosomatic Research

TL;DR: MBSR is moderately effective in reducing stress, depression, anxiety and distress and in ameliorating the quality of life of healthy individuals; however, more research is warranted to identify the most effective elements of MBSR.

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1,031 citations

Journal Article•DOI•

Effectiveness of online mindfulness-based interventions in improving mental health: A review and meta-analysis of randomised controlled trials

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M.P.J. Spijkerman¹, Wendy Theresia Maria Pots¹, Ernst Thomas Bohlmeijer¹•Institutions (1)

University of Twente¹

01 Apr 2016-Clinical Psychology Review

TL;DR: It is shown that online MBIs have potential to contribute to improving mental health outcomes, particularly stress, and that effect sizes for stress were significantly moderated by the number of intervention sessions.

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605 citations

Cites background from "Mindfulness-based therapy: A compre..."

...…al., 2010; Hofmann et al., 2010; Klainin-Yobas et al., 2012; Powers, Zum Vörde Sive Vörding, & Emmelkamp, 2009; Strauss et al., 2014; Veehof et al., 2011), there are also meta-analyses which indicate that higher quality studies yield smaller effect sizes (A-Tjak et al., 2015; Khoury et al., 2013)....
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..., 2011), there are also meta-analyses which indicate that higher quality studies yield smaller effect sizes (A-Tjak et al., 2015; Khoury et al., 2013)....
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Journal Article•DOI•

Mindfulness-based interventions for psychiatric disorders: A systematic review and meta-analysis

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Simon B. Goldberg¹, Raymond P. Tucker², Preston A. Greene, Richard J. Davidson¹, Bruce E. Wampold¹, David J. Kearney, Tracy L. Simpson³ - Show less +3 more•Institutions (3)

University of Wisconsin-Madison¹, Louisiana State University², Center for Excellence in Education³

01 Feb 2018-Clinical Psychology Review

TL;DR: Results support the notion that mindfulness-based interventions hold promise as evidence-based treatments and effects on specific disorder subgroups showed the most consistent evidence in support of mindfulness for depression, pain conditions, smoking, and addictive disorders.

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604 citations

Cites background or result from "Mindfulness-based therapy: A compre..."

...While other comprehensive meta-analyses have suggested that mindfulness-based interventions can impact clinical outcomes (e.g., anxiety, depression; Khoury et al., 2013), and several meta-analyses have examined the evidence for specific psychiatric conditions (e.g., Attention Deficit and…...
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...…in the included studies are consistent with several other symptom- or disorder-specific meta-analytic reviews (e.g., Cairncross &Miller, 2016; Khoury et al., 2013; Khoury, Lecomte, Gaudiano, & Paquin, 2013; Piet & Hougaard, 2011) as well as with a comprehensive review in child and adolescent…...
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...order-specific meta-analytic reviews (e.g., Cairncross &Miller, 2016; Khoury et al., 2013; Khoury, Lecomte, Gaudiano, & Paquin, 2013; Piet & Hougaard, 2011) as well as with a comprehensive review in child and adolescent samples (Zoogman, Goldberg, Hoyt, &Miller, 2015)....
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...While other comprehensive meta-analyses have suggested that mindfulness-based interventions can impact clinical outcomes (e.g., anxiety, depression; Khoury et al., 2013), and several meta-analyses have examined the evidence for specific psychiatric conditions (e....
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Journal Article•DOI•

Mindfulness Interventions with Youth: A Meta-Analysis

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Sarah Zoogman¹, Simon B. Goldberg², William T. Hoyt², Lisa Miller¹•Institutions (2)

Columbia University¹, University of Wisconsin-Madison²

01 Apr 2015-Mindfulness

TL;DR: The first published meta-analysis of the burgeoning literature on mindfulness meditation with youth (conducted between 2004 and 2011) identifies specific outcomes and sub-populations for whom mindfulness may be particularly helpful as mentioned in this paper.

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Abstract: Mindfulness meditation is a well-validated intervention for symptoms of depression and anxiety disorders in adults, with meta-analyses showing moderate effect sizes. This study marks the first published meta-analysis of the burgeoning literature on mindfulness meditation with youth (conducted between 2004 and 2011) and identifies specific outcomes and sub-populations for whom mindfulness may be particularly helpful. Inclusion criteria were peer-reviewed journal articles published in English, study participants under 18 years of age, and a description in the methods section of mindfulness as the chief component of an intervention. A systematic search was conducted, of which upon review, 20 articles met inclusion criteria. Mindfulness interventions with youth overall were found to be helpful and not to carry iatrogenic harm, with the primary omnibus effect size (del) in the small to moderate range (0.23, p < .0001), indicating the superiority of mindfulness treatments over active control comparison conditions. A significantly larger effect size was found on psychological symptoms compared to other dependent variable types (0.37 vs. 0.21, p = .028), and for studies drawn from clinical samples compared to non-clinical sample (0.50 vs. 0.20, p = .024). Mindfulness appears to be a promising intervention modality for youth. Although to date the majority of studies on mindfulness with youth engage generally healthy participants recruited from schools, the findings of this meta-analysis suggest that future research might focus on youth in clinical settings and target symptoms of psychopathology.

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539 citations

Cites background or methods from "Mindfulness-based therapy: A compre..."

...Meta-analyses conducted over reports of clinical trials of mindfulness with adults generally show medium effect sizes (de Vibe et al. 2012; Khoury et al. 2013)....
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...…et al. 1995) Mindfulness interventions with adults have been shown to be beneficial for a variety of mental health and physical health outcomes, including anxiety, depression, and stress (Baer 2003; de Vibe et al. 2012; Greeson 2009; Grossman et al. 2004; Hofmann et al. 2010; Khoury et al. 2013)....
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...…of mindfulness interventions with adults have shown a range of effect sizes (Baer 2003; Bohlmeijer et al. 2010; de Vibe et al. 2012; Grossman et al. 2004; Hofmann et al. 2010; Khoury et al. 2013; Klainin-Yobas et al. 2011), with most studies reporting a medium effect size (Cohen’s d =0.30–0.60)....
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...Khoury et al. (2013) reviewed 209 controlled and uncontrolled studies using mindfulnessbased therapies (MBT; e.g., MBSR, MBCT) and found moderate effect sizes across a range of psychological problems, especially anxiety, depression, and stress....
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References

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Journal Article•DOI•

Measuring inconsistency in meta-analyses

[...]

Julian P T Higgins¹, Simon G. Thompson¹, Jonathan J Deeks, Douglas G. Altman•Institutions (1)

University of Cambridge¹

04 Sep 2003-BMJ

TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.

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Abstract: Cochrane Reviews have recently started including the quantity I 2 to help readers assess the consistency of the results of studies in meta-analyses. What does this new quantity mean, and why is assessment of heterogeneity so important to clinical practice? Systematic reviews and meta-analyses can provide convincing and reliable evidence relevant to many aspects of medicine and health care.1 Their value is especially clear when the results of the studies they include show clinically important effects of similar magnitude. However, the conclusions are less clear when the included studies have differing results. In an attempt to establish whether studies are consistent, reports of meta-analyses commonly present a statistical test of heterogeneity. The test seeks to determine whether there are genuine differences underlying the results of the studies (heterogeneity), or whether the variation in findings is compatible with chance alone (homogeneity). However, the test is susceptible to the number of trials included in the meta-analysis. We have developed a new quantity, I 2, which we believe gives a better measure of the consistency between trials in a meta-analysis. Assessment of the consistency of effects across studies is an essential part of meta-analysis. Unless we know how consistent the results of studies are, we cannot determine the generalisability of the findings of the meta-analysis. Indeed, several hierarchical systems for grading evidence state that the results of studies must be consistent or homogeneous to obtain the highest grading.2–4 Tests for heterogeneity are commonly used to decide on methods for combining studies and for concluding consistency or inconsistency of findings.5 6 But what does the test achieve in practice, and how should the resulting P values be interpreted? A test for heterogeneity examines the null hypothesis that all studies are evaluating the same effect. The usual test statistic …

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45,105 citations

Journal Article•DOI•

Assessing the quality of reports of randomized clinical trials : is blinding necessary?

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Alejandro R. Jadad¹, R. A. Moore¹, Dawn Carroll¹, C. Jenkinson¹, David Reynolds¹, David J. Gavaghan¹, Henry J McQuay¹ - Show less +3 more•Institutions (1)

University of Oxford¹

01 Feb 1996-Controlled Clinical Trials

TL;DR: An instrument to assess the quality of reports of randomized clinical trials (RCTs) in pain research is described and its use to determine the effect of rater blinding on the assessments of quality is described.

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15,740 citations

Book•

Introduction to Meta-Analysis

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Michael Borenstein, Larry V. Hedges¹, Julian P T Higgins², Hannah R. Rothstein³•Institutions (3)

Northwestern University¹, Medical Research Council², Baruch College³

27 Apr 2009

10,518 citations

Book•

Cognitive-Behavioral Treatment of Borderline Personality Disorder

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Marsha M. Linehan¹•Institutions (1)

University of Washington¹

01 Jan 1993

TL;DR: The treatment of Borderline personality disorder (BPD) has been studied extensively in the literature as discussed by the authors, with a focus on the treatment of the behavioral patterns of patients with BPD.

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Abstract: Part I: Theory and Concepts Borderline Personality Disorder: Concepts, Controversies, and Definitions Dialectical and Biosocial Underpinnings of Treatment Behavioral Patterns: Dialectical Dilemmas in the Treatment of Borderline Patients Part II: Treatment Overview and Goals Overview of Treatment: Targets, Strategies, and Assumptions in a Nutshell Behavioral Targets in Treatment: Behaviors to Increase and Decrease Structuring Treatment around Target Behaviors: Who Treats What and When Part III: Basic Treatment Strategies Dialectical Treatment Strategies Core Strategies: Validation Core Strategies: Problem Solving Change Procedures: Contingency Procedures of Managing Contingencies and Observing Limits Change Procedures: Skills Training, Exposure, Cognitive Modification Stylistic Strategies: Balancing Communication Case Management Strategies: Interacting with the Community Part IV: Strategies for Specific Tasks Structural Strategies Special Treatment Strategies Appendix: Suggesting Reading References Index

...read moreread less

6,378 citations

Book•

Meta-analytic procedures for social research

[...]

Robert Rosenthal¹•Institutions (1)

Harvard University¹

01 Jan 1984

TL;DR: In this paper, the authors define research results, retrieve and assess research results and compare and combine research results to combine probabilities, and evaluate meta-analytic procedures and meta-Analytic results.

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Abstract: Introduction Defining Research Results Retrieving and Assessing Research Results Comparing and Combining Research Results Combining Probabilities Illustrations of Meta-Analytic Procedures The Evaluation of Meta-Analytic Procedures and Meta-Analytic Results

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5,181 citations