MiR-21 Indicates Poor Prognosis in Tongue Squamous Cell Carcinomas as an Apoptosis Inhibitor
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...Its expression is obviously up-regulated in diverse types of malignancies such as glioblastoma multiforme [34], breast cancer [11,13], lung cancer [13,14,35–37], esophageal cancer [17], gastrointestinal cancer [13,38,39], hepatocellular cancer [16], cholangiocarcinoma [15], pancreatic cancer [13,19], prostate cancer [13], bladder cancer [24], ovarian cancer [20], NK-cell lymphoma [21], laryngeal carcinoma [22], and tongue squamous cell carcinomas [23]....
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...Numbers marked on top (1-10) represent the number of each specimen....
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...They regulate gene expression by repressing mRNA translation or cleaving target mRNA (5, 6)....
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...Numbers marked on top (1-10) represent the number of each specimen....
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...Changes of miRNA profile in many types of body fluids may reflect potential physiologic and/or pathologic conditions (38, 39), and thus, may be applicable in clinics....
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