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Models of human lung airways and their application to inhaled particle deposition
Hsu-Chi Yeh,G. M. Schum +1 more
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In this paper, the authors developed a model of the human respiratory tract based on detailed morphometric measurements of a silicone rubber cast of the tracheobronchial airways, which contained geometrical parameters, including airway segment diameters, lengths, branching angles and angles of inclination to gravity.About:
This article is published in Bulletin of Mathematical Biology.The article was published on 1980-01-01. It has received 556 citations till now. The article focuses on the topics: Particle deposition.read more
Citations
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Indoor aerosols: from personal exposure to risk assessment
Lidia Morawska,Alireza Afshari,G. N. Bae,Giorgio Buonanno,Giorgio Buonanno,Christopher Y.H. Chao,Otto Hänninen,Werner Hofmann,Christina Isaxon,E.R. Jayaratne,Pertti Pasanen,Tunga Salthammer,Michael S. Waring,Aneta Wierzbicka +13 more
TL;DR: In this article, the authors reviewed existing literature to identify state-of-the-art experimental techniques used for personal exposure assessment; compare exposure levels reported for domestic/school settings in different countries, assess the contribution of outdoor background vs indoor sources to personal exposure; and examine scientific understanding of the risks posed by personal exposure to indoor aerosols.
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Cell number and distribution in human and rat airways.
TL;DR: Airway surface area from trachea to bronchioles was 2,471 +/- 320 and 27.2 +/- 1.7 cm2 in human and rat lungs, respectively, less than half of the estimates based on current lung models.
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Thoracic and respirable particle definitions for human health risk assessment
TL;DR: Estimates show less penetration of coarse particulate matter into the thoracic and gas exchange regions of the respiratory tract than current size-selective criteria, which is most dependent on route of breathing.
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Modelling inhaled particle deposition in the human lung—A review
TL;DR: A review of different conceptual whole lung models to determine deposition in bronchial and acinar airway generations, and to compare the deposition patterns predicted by these models is presented in this paper.
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Monte Carlo modeling of aerosol deposition in human lungs. Part I: Simulation of particle transport in a stochastic lung structure
László Koblinger,Werner Hofmann +1 more
TL;DR: In this paper, a stochastic model for the calculation of aerosol deposition in human lungs has been developed, where the geometry of the airways along the path of an inhaled particle is selected randomly, whereas deposition probabilities are computed by deterministic formulae.
References
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Journal Article
Deposition and retention models for internal dosimetry of the human respiratory tract. Task group on lung dynamics.
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Models of the human bronchial tree.
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On the removal of air-borne droplets by the human respiratory tract: I. The lung
TL;DR: The calculated results also give information on the amounts deposited in various regions as well as the amounts retained in different fractions of expired air.
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Anatomic models of the tracheobronchial and pulmonary regions of the rat
TL;DR: Models of the lung airways of a rat were developed from complete measurements of the tracheobronchial airways andphasis was placed on the “Typical Path Lung Model” which used one typical pathway to represent either a whole lung or a lobe of the lungs.