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MODELTEST: testing the model of DNA substitution.

David Posada, +1 more
- 01 Jan 1998 - 
- Vol. 14, Iss: 9, pp 817-818
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TLDR
The program MODELTEST uses log likelihood scores to establish the model of DNA evolution that best fits the data.
Abstract
Summary: The program MODELTEST uses log likelihood scores to establish the model of DNA evolution that best fits the data. Availability: The MODELTEST package, including the source code and some documentation is available at http://bioag.byu.edu/zoology/crandall―lab/modeltest.html. Contact: dp47@email.byu.edu.

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Citations
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Journal ArticleDOI

HyPhy: hypothesis testing using phylogenies

TL;DR: The HyPhypackage is designed to provide a flexible and unified platform for carrying out likelihood-based analyses on multiple alignments of molecular sequence data, with the emphasis on studies of rates and patterns of sequence evolution.
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Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome

TL;DR: This study illustrates how combining comparative metagenomics with gnotobiotic mouse models and specific dietary manipulations can disclose the niches of previously uncharacterized members of the gut microbiota.
Journal ArticleDOI

Ultrafast Approximation for Phylogenetic Bootstrap

TL;DR: This work proposes an ultrafast bootstrap approximation approach (UFBoot) to compute the support of phylogenetic groups in maximum likelihood (ML) based trees and offers an efficient and easy-to-use software to perform the UFBoot analysis with ML tree inference.
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Antigenic and Genetic Characteristics of Swine-Origin 2009 A(H1N1) Influenza Viruses Circulating in Humans

Rebecca Garten, +62 more
- 10 Jul 2009 - 
TL;DR: The lack of similarity between the 2009 A(H1N1) virus and its nearest relatives indicates that its gene segments have been circulating undetected for an extended period as mentioned in this paper.
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Approximate likelihood-ratio test for branches : A fast, accurate, and powerful alternative

TL;DR: A new, fast, approximate likelihood-ratio test (aLRT) for branches is presented here as a competitive alternative to nonparametric bootstrap and Bayesian estimation of branch support and is shown to be accurate, powerful, and robust to certain violations of model assumptions.
References
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Journal ArticleDOI

A new look at the statistical model identification

TL;DR: In this article, a new estimate minimum information theoretical criterion estimate (MAICE) is introduced for the purpose of statistical identification, which is free from the ambiguities inherent in the application of conventional hypothesis testing procedure.
Journal ArticleDOI

A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences.

TL;DR: Some examples were worked out using reported globin sequences to show that synonymous substitutions occur at much higher rates than amino acid-altering substitutions in evolution.
Journal ArticleDOI

Dating of the human-ape splitting by a molecular clock of mitochondrial DNA.

TL;DR: A new statistical method for estimating divergence dates of species from DNA sequence data by a molecular clock approach is developed, and this dating may pose a problem for the widely believed hypothesis that the bipedal creatureAustralopithecus afarensis, which lived some 3.7 million years ago, was ancestral to man and evolved after the human-ape splitting.
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