Journal ArticleDOI
Modifying role of Phyllanthus emblica and ascorbic acid against nickel clastogenicity in mice.
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Aqueous extract of edible dried fruits of Phyllanthus emblica was fed to Mus musculus for seven consecutive days prior to treatment with different doses of nickel chloride, finding the greater efficacy of the fruit extract could be due to the interaction of its various natural components rather than to any single constituent.About:
This article is published in Cancer Letters.The article was published on 1991-07-26. It has received 59 citations till now. The article focuses on the topics: Dried fruit & Ascorbic acid.read more
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Review on some plants of Indian traditional medicine with antioxidant activity.
Paolo Scartezzini,Ester Speroni +1 more
TL;DR: Seven plants contain antioxidant principles, that can explain and justify their use in traditional medicine in the past as well as the present, and are viewed for their historical, etymological, morphological, phytochemical and pharmacological aspects.
Journal Article
Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (groups 1, 2A and 2B) the summary report of the 6^ collaborative study by CSGMT/JEMS MMS. Collaborative study of the Micronucleus Group Test
TL;DR: Structural-activity relationship analysis suggested that the micronucleus assay is more sensitive to the genetic toxicity of some classes of chemicals than to those carcinogens with stronger evidence human carcinogenicity.
Journal ArticleDOI
Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (groups 1, 2A and 2B) the summary report of the 6th collaborative study by CSGMT/JEMS MMS. Collaborative Study of the Micronucleus Group Test. Mammalian Mutagenicity Study Group.
Takeshi Morita,Norihide Asano,Takumi Awogi,Yu F. Sasaki,Sei-ichi Sato,Hiroyasu Shimada,Sizuyo Sutou,Takayoshi Suzuki,Akihiro Wakata,Toshio Sofuni,Makoto Hayashi +10 more
TL;DR: In the 6th MMS/CSGMT collaborative study as mentioned in this paper, IARC groups 1 (human carcinogen), 2A (probable human carcinogen) and 2B (possible human carcinogens) were selected from 100 commercially available chemicals and chemical groups on which there was little or no micronucleus assay data.
Journal ArticleDOI
A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins.
TL;DR: There is no convincing evidence that any genotoxic rodent carcinogens or in vivo genotoxins would remain undetected in an in vitro test battery consisting of Ames+MNvit.
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Augmentation of murine natural killer cell and antibody dependent cellular cytotoxicity activities by Phyllanthus emblica, a new immunomodulator.
K Suresh,Damodaran Vasudevan +1 more