Molecular Characterization of Basal-Like and Non-Basal-Like Triple-Negative Breast Cancer
Citations
1,777 citations
1,457 citations
Cites background from "Molecular Characterization of Basal..."
...Although a majority of triple negative breast cancers show the basal-like subtype [49], the distinction between these and other types of triple negative breast cancer is important for choice of chemotherapy in that carboplatin is as by gest on M ay 7, 2015 http://annofordjournals....
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1,259 citations
Cites background from "Molecular Characterization of Basal..."
...…it has previously been appreciated that basal-like breast cancers (the majority subset of triple-negative breast cancers) form a distinct subtype (Prat et al., 2013; Cancer Genome Atlas Research Network, 2012c), the findings here provide a more refined, quantitative picture of the extent of…...
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...Although it has previously been appreciated that basal-like breast cancers (the majority subset of triple-negative breast cancers) form a distinct subtype (Prat et al., 2013; Cancer Genome Atlas Research Network, 2012c), the findings here provide a more refined, quantitative picture of the extent of difference from luminal and basal-like breast cancers....
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927 citations
Cites methods from "Molecular Characterization of Basal..."
...In addition, basal-like 1 and basal-like 2 tumors are not readily distinguishable by hierarchical clustering of public TNBC datasets using Lehmann's gene signatures (32), despite demonstration of molecular heterogeneity beyond the classic intrinsic subtypes....
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745 citations
Cites background from "Molecular Characterization of Basal..."
...By gene expression analysis, 70% to 80% of TNBCs display a basal-like profile, whereas the rest are a mix of other subtypes.(24) Other subclassifications have been suggested(25) and are undergoing clinical validation....
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References
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