Molecular Docking: Approaches, Types, Applications and Basic Challenges
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"Molecular Docking: Approaches, Type..." refers methods in this paper
...This can be made possible using scoring function of software [4]....
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1,120 citations
"Molecular Docking: Approaches, Type..." refers background in this paper
...Docking in combination with scoring function can be used to evaluate large databases for finding out potent drug candidate in silico, which can target the molecule of interest [8]....
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433 citations
"Molecular Docking: Approaches, Type..." refers background or methods in this paper
...This can be used to develop more potent, selective and efficient drug candidates [5,7]....
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...To overcome this problem, different scoring functions are employed such as consensus scoring; appliance of number of score functions to the same docked pose in order to eliminate false positives [5]....
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...This approach is rather quick and involves the rapid scanning of numerous thousands of ligands in a few seconds to find out the possible binding properties of ligand on target molecular surface [5,6]....
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301 citations
"Molecular Docking: Approaches, Type..." refers background in this paper
...Molecular docking is an attractive scaffold to understand drugbiomolecular interactions for the rational drug design and discovery, as well as in the mechanistic study by placing a molecule (ligand) into the preferred binding site of the target specific region of the DNA/protein (receptor) mainly in a non-covalent fashion to form a stable complex of potential efficacy and more specificity [1,2]....
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