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Journal ArticleDOI

Molecular rearrangements of 4-iminomethyl-1,2,3-triazoles. Replacement of 1-aryl substituents in 1H-1,2,3-triazole-4-carbaldehydes

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TLDR
In this article, the two structural isomers, 4 and 5, of 1-substituted-4-iminomethyl-1,2,3-triazoles are interconvertible when heated in dimethyl sulfoxide at 80°.
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This article is published in Journal of Heterocyclic Chemistry.The article was published on 1990-11-01. It has received 38 citations till now. The article focuses on the topics: Nitrile & 1,2,3-Triazole.

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Journal ArticleDOI

1,2,3-Triazole and its derivatives. Development of methods for the formation of the triazole ring

TL;DR: In this paper, the synthetic routes to substituted 1,2,3-triazoles, including those containing functional groups, based on cyclisation of various nitrogen compounds published during the last 15 years are described.
Journal ArticleDOI

Synthesis and investigation of tuberculosis inhibition activities of some 1,2,3-triazole derivatives.

TL;DR: In this study, alpha-diazo-beta-oxoaldehyde compounds were condensed with different amines to yield 4-acyl-1H-1,2,3-triazole derivatives, which were investigated for their inhibition activities against tuberculosis.
Journal ArticleDOI

Synthesis of novel 1,2,3-triazole substituted-N-alkyl/aryl nitrone derivatives, their anti-inflammatory and anticancer activity

TL;DR: A series of novel 1,2,3-triazole substituted N-phenyl nitrone derivatives 5a-e and 6a-p exhibited significant inhibition of IL-1β secretion as a measure of anti-inflammatory activity against various cancer cell lines.
Journal ArticleDOI

Regioselective synthesis of 1,2,3-triazole derivatives via 1,3-dipolar cycloaddition reactions in water.

TL;DR: In this paper, arylacetylene with an azide in hot water gave 1,4-disubstituted 1,2,3-triazoles in high yields, while similar reaction between a terminal aliphatic alkyne and an azides (except m-nitroazidobenzene) afforded a mixture of regioisomers with the ratio of 1, 4 to 1,5-isomers ranging from 3 : 1 to 28.6 : 1.
Book ChapterDOI

4.01 – 1,2,3-Triazoles

Wei-Qiang Fan
References
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Journal ArticleDOI

Molecular rearrangements of five-membered ring heteromonocycles

TL;DR: In this article, the authors classified molecular rearrangements of five-membered ring heterocycles into five categories based on the number of participating side-chain atoms: Dimroth rearrangement, Dimroth contraction-ring expansion (DRCE), Dimroth expansion, Cornforth, Boulton-Katritzky, and bond-switch rearranging.
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