Movement disorders: Indian scenario: a clinico-genetic review.
Citations
23 citations
Cites background from "Movement disorders: Indian scenario..."
...However, in the Asian-Indian population, studies report absence of mutations in SNCA/α-synuclein gene while mutations in DJ-1, PINK1 and LRRK2 genes are rare [39, 40]; hence, we did not choose a genetic model of the disease....
[...]
10 citations
Cites background from "Movement disorders: Indian scenario..."
..., G2019S) primarily identified in the white population—and excluded the role of these LRRK2 variants in the Indian PD population.(23,25,50,51) Here, we performed the first comprehensive study using targeted sequencing in Indian PD patients, which led to the identification of populationspecific novel variants and underscores the relevance of allelic heterogeneity in PD....
[...]
9 citations
3 citations
Cites background from "Movement disorders: Indian scenario..."
...Das contributed on the epidemiology of various movement disorders.[18] The other important contribution of Indian literature has been on SCA-12....
[...]
2 citations
References
1,793 citations
"Movement disorders: Indian scenario..." refers background in this paper
...Recent genome wide association studies on Asian and Caucasian populations have identified a number of associated genes in PD including ethnicity specific susceptible genes.[68,69] Majority of the mutations in the...
[...]
1,206 citations
"Movement disorders: Indian scenario..." refers background in this paper
...Recent genome wide association studies on Asian and Caucasian populations have identified a number of associated genes in PD including ethnicity specific susceptible genes.[68,69] Majority of the mutations in the...
[...]
901 citations
"Movement disorders: Indian scenario..." refers background in this paper
...Eighteen genetic loci with 13 underlying genes have been identified till date for PD, however, only 6 genes [Alpha‐synuclein (SNCA), Leucine rich repeat kinase‐2 (LRRK2), Parkin, PTEN induced putative kinase 1 (PINK1), DJ‐1, ATPase type 13A2 (ATP13A2)] could be conclusively proved to be causal towards the disease.[45] In India, candidate gene studies have been performed on SNCA,[46,47] Parkin,[48‐52] PINK1,[53] DJ‐1,[54,55] and LRRK2[47,56‐59] only [Table 2], with the maximum study being reported on Parkin....
[...]
218 citations
130 citations
"Movement disorders: Indian scenario..." refers background or result in this paper
...Higher prevalence of PD among Parsi population is due to higher aged population when compared to national population [Table 1].[12] However the prevalence of PD is lower than many Caucasian populations....
[...]
...Region Author Year of study Population surveyed (R/U) Crude prevalence rate Age adjusted rate West India([12]) Bharucha et al....
[...]