Journal ArticleDOI
Movement disorders: Indian scenario: a clinico-genetic review.
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TLDR
Common problems of MDs in India with regard to epidemiology, clinical features and genetics are highlighted.Abstract:
Movement disorder (MD) is an important branch of neurology and has great potentiality in management because of improved diagnosis and therapeutic strategies. Over the last three decades, emphasis has been laid on the evaluation of various MDs in India by a limited number of interested neurologists and basic scientists. In this review, we want to highlight common problems of MDs in India with regard to epidemiology, clinical features and genetics.read more
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Admixing of MPTP-Resistant and Susceptible Mice Strains Augments Nigrostriatal Neuronal Correlates to Resist MPTP-Induced Neurodegeneration
TL;DR: The core neuroanatomical features of resilience against PD and evidence for ethnicity-based differential prevalence are presented and similar neural correlates of resilience are envisaged in the Anglo-Indian population.
Journal ArticleDOI
Understanding the role of genetic variability in LRRK2 in Indian population
Asha Kishore,Ashwin Ashok Kumar Sreelatha,Marc Sturm,Felix von-Zweydorf,Felix von-Zweydorf,Lasse Pihlstrøm,Francesco Raimondi,Robert B. Russell,Peter Lichtner,Moinak Banerjee,Syam Krishnan,Roopa Rajan,Divya Kalikavil Puthenveedu,Sun Ju Chung,Peter Bauer,Olaf Riess,Christian Johannes Gloeckner,Rejko Krüger,Thomas Gasser,Thomas Gasser,Manu Sharma +20 more
TL;DR: Genetic variability in LRRK2 has been unequivocally established as a major risk factor for familial and sporadic forms of PD in ethnically diverse populations.
Journal ArticleDOI
Perspectives on Translational Genomics and Public Health in India.
TL;DR: The relevance, importance, and translational impediments of contemporary advances to implement public health principles into practice has neither been attempted nor impacted on disease burden or the authors' preparedness to prevent eventualities.
Journal ArticleDOI
The chronicles of modern movement disorders in India
TL;DR: A chronicle of Indian Movement Disorders is written based on personal interviews with various senior Movement Disorder specialists of India as mentioned in this paper, which is a right time to look back into the history of Indian Neurology with specific reference to the Movement Disorders and pen down these chronicles since the inception of modern neurology in India.
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Descriptive epidemiological study on patients with movement disorders, with emphasis on Parkinson's disease.
TL;DR: The most frequent diagnosis was Parkinson's disease, followed by essential tremor and dystonia, and most patients were over 60 years of age, white, married and teachers.
References
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Journal Article
Neuroepidemiology of major neurological disorders in rural Bengal.
TL;DR: Age and sex specific disease prevalence shows female dominance with maximum cases in 4 fourth decade and age specific prevalence disease showed progressive increase in rate with advancing age upto 4th decade followed by a slightly decrease plateau upto 60 years of age and then sharp decline.
Journal Article
Epidemiological study of neurological disorders in a rural population of Eastern India
Shankar Prasad Saha,Sushanta Bhattacharya,Shyamal Kumar Das,Bibekananda Maity,Trishit Roy,D K Raut +5 more
TL;DR: Prevalence of headache, epilepsy, stroke and Parkinson's disease was lower than that of in the Western countries, and different inclusion criteria, multiethnicity, different environmental factors, poor medical facility and insufficient number of aged population may be responsible for lower prevalence.
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Epidemiology of Parkinson disease in the city of Kolkata, India: A community-based study
Shambaditya Das,A.K. Misra,Biman Kanti Ray,Avijit Hazra,Malay Ghosal,Arijit Chaudhuri,Trishit Roy,Tapas Kumar Banerjee,D K Raut +8 more
TL;DR: This study documented lower prevalence and incidence of PD in the city of Kolkata, India as compared with Caucasian and a few Oriental populations and the mortality rates were comparable.
Journal ArticleDOI
Environmental and familial risk factors of Parkinsons disease: case-control study.
Jaya Sanyal,Debashis Chakraborty,Biswanath Sarkar,Tapas Kumar Banerjee,Subhash Chandra Mukherjee,Bidhan Chandra Ray,Vadlamudi Raghavendra Rao +6 more
TL;DR: Results of this study support the hypothesis of multifactorial etiology of PD with environmental factors acting on a genetically susceptible host.
Journal ArticleDOI
Prevalence of Essential Tremor in the Parsi Community of Bombay, India
TL;DR: A door-to-door survey for neurologic diseases was conducted in a community of 14,010 people (Parsis living in colonies in Bombay, India) and is the first community-based survey for essential tremor in Asia.