Multiplexed ion beam imaging of human breast tumors
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1,391 citations
Cites background or methods from "Multiplexed ion beam imaging of hum..."
...…2014; Lubeck et al., 2014; Shah et al., 2016; Ståhl et al., 2016); the distribution of scores of proteins at cellular or sub-cellular resolution (Angelo et al., 2014; Chen et al., 2015a; Giesen et al., 2014; Hama et al., 2011; Susaki et al., 2014; Yang et al., 2014); various aspects of…...
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..., 2014) and Mass Ion Bean Imaging (MIBI) (Angelo et al., 2014), involve staining a tissue specimen with antibodies, each labeled with a barcode of heavy metals, and rastering across the sample to measure the proteins in each ‘pixel’....
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..., 2016) or protein staining (Angelo et al., 2014; Giesen et al., 2014), it should be possible to spatially map multiple cell types at once based on expression signatures to see how they relate to each other and to connect them with cell types defined by morphology or function....
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...Some approaches for protein detection, such as Imaging Mass Cytometry (Giesen et al., 2014) and Mass Ion Bean Imaging (Angelo et al., 2014), involve staining a tissue specimen with antibodies, each labeled with a barcode of heavy metals, and rastering across the sample to measure the proteins in each ’pixel’....
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...Some approaches for protein detection, such as Imaging Mass Cytometry (Giesen et al., 2014) and Mass Ion Bean Imaging (Angelo et al., 2014), involve staining a tissue specimen with antibodies, each labeled with a barcode of heavy metals, and rastering across the sample to measure the proteins in…...
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888 citations
Cites background from "Multiplexed ion beam imaging of hum..."
...Another approach, called 782 Cell 165, May 5, 2016 multiplexed ion beam imaging (MIBI), uses an ion beam to liberate metal ion reporters, which are quantified by mass spectrometry (Angelo et al., 2014)....
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...782 Cell 165, May 5, 2016 multiplexed ion beam imaging (MIBI), uses an ion beam to liberate metal ion reporters, which are quantified by mass spectrometry (Angelo et al., 2014)....
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References
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