Myoclonus and cerebellar ataxia following Coronavirus Disease 2019 (COVID-19).
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TLDR
Within the movement disorder spectrum, myoclonus has been observed as a COVID-19-related feature in several patients, and different neurological symptoms have been described, either directly or indirectly caused by CO VID-19.Citations
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Myoclonus and cerebellar ataxia associated with COVID-19: a case report and systematic review.
TL;DR: A case and systematic review of myoclonus and cerebellar ataxia associated with COVID-19 is presented in this paper, where the authors identify 51 cases associated with the coronavirus disease 2019 pandemic.
Journal ArticleDOI
Cytokine storm induced by SARS-CoV-2 infection: The spectrum of its neurological manifestations.
Parisorn Thepmankorn,John R. Bach,Ahmed Lasfar,Xilin Zhao,Sami Souayah,Zhao Zhong Chong,Nizar Souayah +6 more
TL;DR: Clinification of the pathogenic mechanisms of SARS-CoV-2 is needed to encourage prompt diagnosis and optimized care, and identifying the presence of cytokine storm in patients with neurological COVID-19 manifestations will facilitate avenues for treatment.
Journal ArticleDOI
Opsoclonus-myoclonus syndrome, a post-infectious neurologic complication of COVID-19: case series and review of literature.
Maziar Emamikhah,Mansoureh Babadi,Mehrnoush Mehrabani,Mehdi Jalili,Maryam Pouranian,Peyman Daraie,Fahimeh Mohaghegh,Sharmin Aghavali,Maryam Zaribafian,Mohammad Rohani +9 more
TL;DR: Seven cases of opsoclonus-myoclonu syndrome presumably para-infectious in nature are reported and their phenomenology, their possible pathophysiological relationship to COVID-19 and diagnostic and treatment strategy in each case are discussed.
Journal ArticleDOI
New-Onset Movement Disorders Associated with COVID-19.
Pedro Brandão,Talyta Cortez Grippe,Danilo Assis Pereira,Renato Puppi Munhoz,Francisco Cardoso +4 more
TL;DR: In this article, the authors identified 93 new-onset movement disorders cases (44 articles) from 200 articles screened in the PubMed/MEDLINE database or reference lists, including myoclonus was present in 63.4% (n = 59), ataxia in 38.7%, rigid-akinetic syndrome in 5.4%, dystonia in 1.1%, chorea in 1, and functional (psychogenic) movement disorders in 3.78%.
Journal ArticleDOI
De Novo Movement Disorders and COVID-19: Exploring the Interface.
Ritwik Ghosh,Uttam Biswas,Dipayan Roy,Dipayan Roy,Alak Pandit,Durjoy Lahiri,Biman Kanti Ray,Julián Benito-León +7 more
TL;DR: Neurological manifestations of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) are being widely documented but movement disorders in the setting of 2019 coronav virus infectious disease (COVID‐19) have been a strikingly less discussed topic.
References
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WHO Declares COVID-19 a Pandemic.
TL;DR: The Director-General of the World Health Organization, Dr. Tedros Adhanom Ghebreyesus, noted that over the past 2 weeks, the number of cases outside China increased 13-fold and theNumber of countries with cases increased threefold, and further increases are expected.
Journal ArticleDOI
Neurological Associations of COVID-19
Mark Ellul,Laura A Benjamin,Bhagteshwar Singh,Suzannah Lant,Benedict D Michael,Benedict D Michael,Ava Easton,Rachel Kneen,Sylviane Defres,James Sejvar,Tom Solomon,Tom Solomon,Tom Solomon +12 more
TL;DR: The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is of a scale not seen since the 1918 influenza pandemic and the proportion of infections leading to neurological disease will probably remain small.
Journal ArticleDOI
Delirium in COVID-19: A case series and exploration of potential mechanisms for central nervous system involvement.
Scott R. Beach,Nathan Praschan,Charlotte Hogan,Samuel Dotson,Flannery Merideth,Nicholas Kontos,Gregory L. Fricchione,Felicia A. Smith +7 more
TL;DR: Delirium should be recognized as a potential feature of infection with SARS-CoV-2 and may be the only presenting symptom, and hospitals should consider adding mental status changes to the list of testing criteria.
Journal ArticleDOI
Generalized myoclonus in COVID-19.
Pablo Rábano-Suárez,Laura Bermejo-Guerrero,Antonio Méndez-Guerrero,Javier Parra-Serrano,Daniel Toledo-Alfocea,Daniel Sánchez-Tejerina,Teresa Santos-Fernández,María Dolores Folgueira-López,Judit Gutiérrez-Gutiérrez,Blanca Ayuso-García,Jesús González de la Aleja,Julián Benito-León +11 more
TL;DR: The 3 cases highlight the occurrence of myoclonus during the COVID-19 pandemic as a post- or para-infectious immune-mediated disorder, however, it cannot rule out that SARS-CoV-2 may spread transneuronally to first- and second-order structures connected with the olfactory bulb.
Journal ArticleDOI
Postinfectious brainstem encephalitis associated with SARS-CoV-2.
Anthony Khoo,Benjamin C Mcloughlin,Sanjay Cheema,Rimona S. Weil,Christian Lambert,Hadi Manji,Michael S. Zandi,Jasper M. Morrow +7 more
TL;DR: Clinical improvement was seen following corticosteroids, highlighting this as a possible treatment in patients where a post-CO VID-19 autoimmune encephalitis is suspected, and a postinfectious brainstem syndrome in a patient with COVID-19 who presented with generalised myoclonus, ocular flutter with convergence spasm and acquired hyperekplexia.
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