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Journal ArticleDOI

Nano-fibrous scaffolds for tissue engineering.

Laura A. Smith, +1 more
- 10 Dec 2004 - 
- Vol. 39, Iss: 3, pp 125-131
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TLDR
Three different approaches toward the formation of nano-fibrous materials have emerged: self-assembly, electrospinning and phase separation; each has a unique set of characteristics, which lends to its development as a scaffolding system.
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This article is published in Colloids and Surfaces B: Biointerfaces.The article was published on 2004-12-10. It has received 609 citations till now. The article focuses on the topics: Extracellular matrix component & Tissue engineering.

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Journal ArticleDOI

Electrospinning: a fascinating fiber fabrication technique.

TL;DR: This review presents an overview of the electrospinning technique with its promising advantages and potential applications, and focuses on varied applications of electrospun fibers in different fields.
Journal ArticleDOI

Electrospinning: A Fascinating Method for the Preparation of Ultrathin Fibers

TL;DR: Electrospinning is a highly versatile method to process solutions or melts, mainly of polymers, into continuous fibers with diameters ranging from a few micrometers to a few nanometers, applicable to virtually every soluble or fusible polymer.
Journal ArticleDOI

The extracellular matrix at a glance

TL;DR: The extracellular matrix is the non-cellular component present within all tissues and organs, and provides not only essential physical scaffolding for the cellular constituents but also initiates crucial biochemical and biomechanical cues that are required for tissue development.
Journal ArticleDOI

Electrospinning of polymeric nanofibers for tissue engineering applications: a review.

TL;DR: Electrospinning is examined by providing a brief description of the theory behind the process, examining the effect of changing the process parameters on fiber morphology, and discussing the potential applications and impacts of electrospinning on the field of tissue engineering.
Journal ArticleDOI

Biomimetic materials for tissue engineering.

TL;DR: Current biomimetic materials approaches in tissue engineering include synthesis to achieve certain compositions or properties similar to those of the extracellular matrix, novel processing technologies to achieve structural features mimicking the ext racellular matrix on various levels, and biologic delivery strategies to recapitulate a signaling cascade or developmental/wound healing program.
References
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Journal Article

Tissue engineering : Frontiers in biotechnology

R. Langer, +1 more
- 01 Jan 1993 - 
Journal ArticleDOI

Nanometre diameter fibres of polymer, produced by electrospinning

TL;DR: More than 20 polymers, including polyethylene oxide, nylon, polyimide, DNA, polyaramid, and polyaniline, have been electrospun in this paper.
PatentDOI

Self-assembly and mineralization of peptide-amphiphile nanofibers

TL;DR: In this paper, pH-induced self-assembly of a peptide-amphiphile was used to make a nanostructured fibrous scaffold reminiscent of extracellular matrix.
Journal ArticleDOI

Role of cell shape in growth control

TL;DR: Cell shape was found to be tightly coupled to DNA synthesis and growth in nontransformed cells, suggesting a mechanism that is important in growth control of mammalian cells, and providing a more fundamental interpretation of such phenomena as density dependent inhibition of cell growth and anchorage dependence.
Journal ArticleDOI

Electrospun nanofibrous structure: A novel scaffold for tissue engineering

TL;DR: A novel poly(D,L-lactide-co-glycolide) (PLGA) structure with a unique architecture produced by an electrospinning process has been developed for tissue-engineering applications, which acts to support and guide cell growth.
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