Nanosystems in Drug Targeting: Opportunities and Challenges
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Cites background from "Nanosystems in Drug Targeting: Oppo..."
...Rapid advances in cell and molecular biology have allowed us to develop a better understanding of the pathophysiology of various diseases [1]....
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Cites background from "Nanosystems in Drug Targeting: Oppo..."
...Various nanosystems, as a result of their larger size, are accumulated at higher concentrations than normal drugs [18]....
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...[18] Vasir JK, Reddy MK, Labhasetwar V....
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...Thus, this natural system can be used for targeting drugs for intracellular infections [18]....
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References
1,247 citations
"Nanosystems in Drug Targeting: Oppo..." refers methods in this paper
...Liposomes have been used as carriers for radioisotopes and contrast agents to be used in diagnostic imaging [ 47 ]....
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1,101 citations
"Nanosystems in Drug Targeting: Oppo..." refers background in this paper
...Liposomes have been extensively investigated as a potential drug delivery system due to the enormous diversity of structure and compositions that can be achieved [ 5 ]....
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...For example, the monoclonal antibodies must bind to the drug/its carrier with their Fc part, so that their antigen binding site (Fab) is free to interact with the antigenic targets on cells [ 5 ]....
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...This has been used for intracellular pathogens such as Leishmania donovani, systemic fungal infections, HIV virus and mycobacterial infections, particularly in immunocompromised patients [ 5 ]....
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