Journal ArticleDOI
Natural History of Subclinical Neovascularization in Nonexudative Age-Related Macular Degeneration Using Swept-Source OCT Angiography
João Rafael de Oliveira Dias,Qinqin Zhang,José M.B. Garcia,Fang Zheng,Fang Zheng,Elie H. Motulsky,Luiz Roisman,Andrew R. Miller,Chieh-Li Chen,Sophie Kubach,Luis de Sisternes,Mary K Durbin,William J. Feuer,Ruikang K. Wang,Giovanni Gregori,Philip J. Rosenfeld +15 more
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TLDR
By 12 months, the risk of exudation was greater for eyes with documented subclinical MNV compared with eyes without detectable MNV, and recommendations include more frequent follow-up and home monitoring.About:
This article is published in Ophthalmology.The article was published on 2017-09-01. It has received 152 citations till now. The article focuses on the topics: Subclinical infection.read more
Citations
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Journal ArticleDOI
Artificial intelligence in retina.
Ursula Schmidt-Erfurth,Amir Sadeghipour,Bianca S. Gerendas,Sebastian M. Waldstein,Hrvoje Bogunovic +4 more
TL;DR: In this paper, a fully automated AI-based system has been proposed for screening of diabetic retinopathy (DR) in diabetic macular and retinal disease using a convolutional neural network.
Journal ArticleDOI
Consensus Nomenclature for Reporting Neovascular Age-Related Macular Degeneration Data: Consensus on Neovascular Age-Related Macular Degeneration Nomenclature Study Group
Richard F. Spaide,Glenn J. Jaffe,David Sarraf,K. Bailey Freund,Srinivas R. Sadda,Giovanni Staurenghi,Nadia K. Waheed,Usha Chakravarthy,Philip J. Rosenfeld,Frank G. Holz,Eric H. Souied,Salomon Y. Cohen,Giuseppe Querques,Kyoko Ohno-Matsui,David S. Boyer,Alain Gaudric,Barbara A Blodi,Caroline R. Baumal,Xiaoxin Li,Gabriel Coscas,Alexander J. Brucker,Lawrence J. Singerman,Phil Luthert,Steffen Schmitz-Valckenberg,Ursula Schmidt-Erfurth,Hans E. Grossniklaus,David J. Wilson,Robyn H. Guymer,Lawrence A. Yannuzzi,Emily Y. Chew,Karl G. Csaky,Jordi Monés,Daniel Pauleikhoff,Ramin Tadayoni,James G. Fujimoto +34 more
TL;DR: The study group suggests that the consensus standards outlined in this article be used in future reported studies of neovascular AMD and clinical practice.
Journal ArticleDOI
OCT angiography and evaluation of the choroid and choroidal vascular disorders.
TL;DR: A review of the salient histological and anatomical features of the choroid, essential for the proper interpretation of in vivo imaging, is followed by a discussion of the fundamental principles of OCTA and the application of this advanced imaging modality to study and understand the Choroid.
Journal ArticleDOI
Predicting conversion to wet age-related macular degeneration using deep learning
Jason Yim,Reena Chopra,Terry Spitz,Jim Winkens,Annette Obika,Christopher Kelly,Harry Askham,Marko Lukic,Josef Huemer,Katrin Fasler,Gabriella Moraes,Clemens Meyer,Marc Wilson,Jonathan Mark Dixon,Cian Hughes,Geraint Rees,Peng T. Khaw,Alan Karthikesalingam,Dominic King,Demis Hassabis,Mustafa Suleyman,Trevor Back,Joseph R. Ledsam,Pearse A. Keane,Jeffrey De Fauw +24 more
TL;DR: In individuals diagnosed with age-related macular degeneration in one eye, a deep learning model can predict progression to the ‘wet’, sight-threatening form of the disease in the second eye within a 6-month time frame, and demonstrates the potential of using AI to predict disease progression.
Journal ArticleDOI
Risk factors for progression of age‐related macular degeneration
Thomas J. Heesterbeek,Laura Lorés-Motta,Carel B. Hoyng,Yara T. E. Lechanteur,Anneke I. den Hollander +4 more
TL;DR: An overview of the current literature investigating phenotypic, demographic, environmental, genetic, and molecular risk factors in age‐related macular degeneration is provided, and the most consistently identified risk factors for disease progression are proposed based on these studies.
References
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Journal ArticleDOI
Clinical Classification of Age-related Macular Degeneration
Frederick L. Ferris,Charles P. Wilkinson,Alan C. Bird,Usha Chakravarthy,Emily Y. Chew,Karl G. Csaky,Srinivas R. Sadda +6 more
TL;DR: The proposed basic clinical classification scale seems to be of value in predicting the risk of late AMD, and incorporating consistent nomenclature into the practice patterns of all eye care providers may improve communication and patient care.
Journal Article
Senile macular degeneration: a histopathologic study.
W R Green,S N Key rd +1 more
TL;DR: The histopathologic features of 176 eyes from 115 patients with senile macular degeneration support the view that older persons with drusen are predisposed to the development of serous detachments, areolar retinal pigment epithelial atrophy, and subretinal pigment intestinal epithelial neovascularization.
Journal ArticleDOI
Depth-resolved imaging of capillary networks in retina and choroid using ultrahigh sensitive optical microangiography
TL;DR: The depth-resolved and detailed ocular perfusion maps within retina and choroid can be obtained from an ultrahigh sensitive optical microangiography (OMAG) that applies the OMAG algorithm along the slow scanning axis to achieve the ultra high sensitive imaging to the slow flows within capillaries.
Journal ArticleDOI
Methods and algorithms for optical coherence tomography-based angiography: a review and comparison.
TL;DR: The purpose of this review is to help readers understand and select appropriate OCT angiography algorithm for use in specific applications and it is found that the method that utilizes complex OCT signal to contrast retinal blood flow delivers the best performance among all the algorithms in terms of image contrast and vessel connectivity.
Journal ArticleDOI
New vessel formation beneath the retinal pigment epithelium in senile eyes.
TL;DR: The purpose of this investigation was to determine the frequency with which new vessel formation beneath the retina can be demonstrated histologically in senile eyes and to describe the associated clinical and histological findings.
Related Papers (5)
Consensus Definition for Atrophy Associated with Age-Related Macular Degeneration on OCT: Classification of Atrophy Report 3.
Srinivas R. Sadda,Robyn H. Guymer,Frank G. Holz,Steffen Schmitz-Valckenberg,Christine A. Curcio,Alan C Bird,Barbara A Blodi,Ferdinando Bottoni,Usha Chakravarthy,Emily Y. Chew,Karl G. Csaky,Ronald P. Danis,Monika Fleckenstein,K. Bailey Freund,Juan E. Grunwald,Carel B. Hoyng,Glenn J. Jaffe,Sandra Liakopoulos,Jordi Monés,Daniel Pauleikhoff,Philip J. Rosenfeld,David Sarraf,Richard F. Spaide,Ramin Tadayoni,Adnan Tufail,Adnan Tufail,Sebastian Wolf,Giovanni Staurenghi +27 more