Neurobiological markers of exercise-related brain plasticity in older adults
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Cites background from "Neurobiological markers of exercise..."
...Furthermore, changes in functional connectivity were associated with changes in BDNF and other growth factors.(68) Although less evidence is available for the effect of exercise interventions in people with cognitive impairments, in one study subjects (n=138) participating in a 24-week selfmonitored home-based walking program were compared to a control group of subjects who received education and usual care....
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...Improved functional connectivity between regions prone to age-related disruption was seen after 12 months of moderate aerobic training, and this was associated with improvements in executive function.(67,68) Furthermore, changes in functional connectivity were associated with changes in BDNF and other growth factors....
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References
115,069 citations
"Neurobiological markers of exercise..." refers background or methods in this paper
...05, sample sizes would have had to been extremely high, with a total N of 280 for BDNF, 600 for IGF-1, and 160 for VEGF (Cohen, 1988)....
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...To approximate the strength of the difference between group tau correlation values, Fisher’s r-to-z transformation was conducted to compare the magnitude of the partial correlations and we report the effect size (q) associated with the difference between correlations (Cohen, 1988)....
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...A Fisher’s Z test on the difference in correlations was not statistically significant (p = .14), however the approximate effect size for the difference in correlations was of medium size, q = .31 (Cohen, 1988)....
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...A Fisher’s Z test on the difference in correlations was not statistically significant (p = .32), and the approximate effect size for the difference in correlations was of small size, q = .19 (Cohen, 1988)....
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...A Fisher’s Z test on the difference in correlations was not statistically significant (p = .11), however the approximate effect size for the difference in correlations was of medium size, q = .37 (Cohen, 1988)....
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33,268 citations
"Neurobiological markers of exercise..." refers background in this paper
...…strong right handedness (since brain organization can vary based on handedness), with a 75% or above on the Edinburgh Handedness Questionnaire (Oldfield, 1971), (2) be between the ages of 55 and 80 years (3) score P 51 on the modified Mini-Mental Status Exam (mMMSE, Stern et al., 1987)), a…...
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...Eligible participants had to (1) demonstrate strong right handedness (since brain organization can vary based on handedness), with a 75% or above on the Edinburgh Handedness Questionnaire (Oldfield, 1971), (2) be between the ages of 55 and 80 years (3) score P 51 on the modified Mini-Mental Status Exam (mMMSE, Stern et al., 1987)), a screening questionnaire to rule out potential neurological pathology, (4) score 3 on the Geriatric Depression Scale (GDS) (Sheikh and Yesavage, 1986), (5) have normal color vision (6) have a corrected visual acuity of at least 20/40 and (7) sign an informed consent....
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...Questionnaire (Oldfield, 1971), (2) be between the ages of 55 and 80 years (3) score P 51 on the modified Mini-Mental Status Exam (mMMSE, Stern et al....
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10,477 citations
9,887 citations
"Neurobiological markers of exercise..." refers methods in this paper
...The following pre-statistics processing was applied: rigid body motion correction using MCFLIRT (Jenkinson et al., 2002), removal of non-brain structures using BET (Smith, 2002), spatial smoothing using a Gaussian kernel of FWHM 6.0-mm, grand-mean intensity normalisation of the entire 4D dataset by a single multiplicative factor, and temporal filtering to restrict the bandwidth of the fMRI signal to .008 < f < .080 Hz....
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..., 2002), removal of non-brain structures using BET (Smith, 2002), spatial smoothing using a Gaussian kernel of FWHM 6....
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...…processing was applied: rigid body motion correction using MCFLIRT (Jenkinson et al., 2002), removal of non-brain structures using BET (Smith, 2002), spatial smoothing using a Gaussian kernel of FWHM 6.0-mm, grand-mean intensity normalisation of the entire 4D dataset by a single…...
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...To create the study-specific template, high-resolution structural images were first skullstripped using BET (Smith, 2002), and manually inspected and corrected for any skull-stripping errors....
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