Neuroimaging in Central Nervous System Lymphoma.
Citations
118 citations
Cites background from "Neuroimaging in Central Nervous Sys..."
...Magnetic resonance imaging (MRI) with gadolinium contrast is the most sensitive imaging modality in the diagnosis of PCNSL. PCNSL is characterized by homogeneous contrast enhancement with well-defined borders13 (Fig....
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...There are 2 prognostic scoring systems developed specifically for PCNSL....
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...Because of its inadequate control of the disease and the risk of neurotoxicity, WBRT alone is no longer routinely recommended for patients with newly diagnosed PCNSL....
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...Although the optimal treatment approach has yet to be established, HD-MTX–based chemotherapy is currently considered the standard induction treatment for newly diagnosed PCNSL. Ongoing randomized trials are investigating different consolidative approaches using high-dose chemotherapy with ASCT, reduced-dose WBRT, or chemotherapy....
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...Age and performance status are the most important prognostic factors for PCNSL....
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80 citations
Cites background from "Neuroimaging in Central Nervous Sys..."
...Despite having some characteristics on conventional MRI, differentiation of the imaging appearances of PCNSL from those of HGG is difficult or even impractical [133, 134]....
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References
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