Neuropathological stageing of Alzheimer-related changes.
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...The severity of co-occurring AD-related pathology was classified according to a procedure permitting differentiation of stages I–VI in the development of neurofibrillary changes and stages A–C in the evolution of -amyloid deposits (Table 2) [6,48]....
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...ries [68]) and the clinical syndrome of AD dementia (estimated prevalence from three epidemiological studies [69–71])....
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References
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"Neuropathological stageing of Alzhe..." refers background in this paper
...Insidious onset and continual progress of dementia in a state of clear consciousness characterize AD [37, 42, 54]....
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"Neuropathological stageing of Alzhe..." refers background in this paper
...NFT and NT, in contrast, exhibit a well-defined pattern [20, 30, 34, 60], permitting differentiation of stages....
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