Journal ArticleDOI
New synthesis of flavanones catalyzed by l-proline
Reads0
Chats0
TLDR
L-Proline is utilized as an efficient organocatalyst for the synthesis of substituted flavanones and chalcones in good yields as mentioned in this paper, which is proved with a variety of substrates ranging from electron-deficient to electron-rich aryl aldehydes and 2-hydroxyacetophenones.About:
This article is published in Tetrahedron Letters.The article was published on 2005-10-10. It has received 68 citations till now.read more
Citations
More filters
Journal ArticleDOI
A comprehensive review on flavanones, the major citrus polyphenols
TL;DR: A review of the current knowledge about flavanones from their occurrence in plants to the bioactivity of their metabolites in humans is presented in this paper, where the authors summarize the current state of the art.
Journal ArticleDOI
Synthesis of chalcones via Claisen–Schmidt condensation reaction catalyzed by acyclic acidic ionic liquids
TL;DR: Some recyclable acyclic SO 3 H-functionalized ionic liquids have been used as catalysts for the synthesis of chalcones by Claisen-Schmidt condensation as discussed by the authors.
Journal ArticleDOI
Identification of natural epimeric flavanone glycosides by NMR spectroscopy
TL;DR: In this paper, the possible stereoisomers of flavanone glycosides were identified by NMR spectroscopy based on the 1 H NMR resonances of two diastereomeric forms of each glycoside.
Journal ArticleDOI
Highly efficient construction of spirocyclic chromanone-pyrrolidines via Cu(I)/TF-BiphamPhos-catalyzed asymmetric 1,3-dipolar cycloaddition.
TL;DR: A facile synthesis of highly functional spiro bearing one unique spiro quarternary and three tertiary stereogenic centers is developed in excellent stereoselectivity for the first time.
Journal ArticleDOI
Asymmetric Cyclization of 2′‐Hydroxychalcones to Flavanones: Catalysis by Chiral Brønsted Acids and Bases
TL;DR: In this paper, the authors investigated the possibility of using camphorsulfonic acid as chiral Bronsted acid catalysts for asymmetric cyclization of 2-hydroxychalcones to flavanones.
References
More filters
Journal ArticleDOI
Proline-Catalyzed Direct Asymmetric Aldol Reactions
TL;DR: The finding that the amino acid proline is an effective asymmetric catalyst for the direct aldol reaction between unmodified acetone and a variety of aldehydes is reported.
Journal ArticleDOI
Direct organocatalytic aldol reactions in buffered aqueous media
TL;DR: In this paper, a prebiotic route to sugars was proposed using cross-aldol reactions catalyzed by cyclic secondary amines in aqueous media, which may provide a direct route to a variety of aldols including carbohydrate derivatives.
Journal ArticleDOI
Zn-Proline catalyzed direct aldol reaction in aqueous media
Tamis Darbre,Miguel Machuqueiro +1 more
TL;DR: In this article, the aldol addition of p-nitrobenzaldehyde and acetone in aqueous medium, giving quantitative yields and enantiomeric excesses up to 56% with 5 mol% of the catalysts at room temperature.
Journal ArticleDOI
Asymmetric aldol reactions in poly(ethylene glycol) catalyzed by L-proline
TL;DR: In this article, a l-proline catalyzed direct aldol reaction between various aldehydes and acetone was achieved using PEG as the solvent with comparable enantioselectivities and yields to those obtained in other solvents.
Journal ArticleDOI
Synthesis of flavanones using nanocrystalline MgO
TL;DR: In this paper, the design and development of a truly nano heterogeneous catalyst for the Claisen-Schmidt condensation of benzaldehydes with 2-hydroxyacetophenone to yield substituted chalcones followed by isomerization to afford flavanones with excellent yields and selectivity is described.