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Open AccessJournal Article

Nicotine receptor partial agonists for smoking cessation.

Kenneth W. Lin
- 01 Oct 2011 - 
- Vol. 84, Iss: 7, pp 769
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TLDR
In head-to-head trials, varenicline appears to be at least as effective as nicotine replacement therapy and bupropion and a large cohort study found no increase in the likelihood of depression or suicidality.
Abstract
Compared with placebo, varenicline more than doubles the chances of successful long-term smoking abstinence. In head-to-head trials, varenicline appears to be at least as effective as nicotine replacement therapy and bupropion (Zyban). The most common adverse effect is nausea, which decreases over time; a large cohort study found no increase in the likelihood of depression or suicidality.

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Guidelines for the Primary Prevention of Stroke A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

TL;DR: Evidence-based recommendations are included for the control of risk factors, interventional approaches to atherosclerotic disease of the cervicocephalic circulation, and antithrombotic treatments for preventing thrombosis and thromboembolic stroke.
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