NMDA receptor-dependent switching between different gamma rhythm-generating microcircuits in entorhinal cortex
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...However, research seems to suggest that differences in frequencies associated with various mechanisms may indeed be important for determining which pathways are most effective under particular circumstances (Middleton et al., 2008)....
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...7, PV interneurons are strongly implicated in the generation of cortical gamma rhythms (Fuchs et al., 2007; Middleton et al., 2008; Cardin et al., 2009; Sohal et al., 2009; Carlen et al., 2012)....
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...As already discussed in section 1.4.7, PV+ interneurons are strongly implicated in the generation of cortical gamma rhythms (Fuchs et al., 2007; Middleton et al., 2008; Cardin et al., 2009; Sohal et al., 2009; Carlen et al., 2012)....
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...The involvement of a specific class of inhibitory interneurons, which expresses the Ca2+ buffer parvalbumin (PV), has been indicated (Fuchs et al., 2007; Middleton et al., 2008; Carlen et al., 2012) and confirmed using optogenetics (Cardin et al., 2009; Sohal et al., 2009)....
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...The involvement of a specific class of inhibitory interneurons, which expresses the Ca buffer parvalbumin (PV), has been indicated (Fuchs et al., 2007; Middleton et al., 2008; Carlen et al., 2012) and confirmed using optogenetics (Cardin et al....
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"NMDA receptor-dependent switching b..." refers background in this paper
...This mechanism can underlie gamma rhythms in a broad range of frequencies from around 20 Hz up to 70 Hz in the hippocampus (8) but cannot support higher frequencies such as those labeled as ‘‘high gamma’’ previously (9)....
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1,625 citations
"NMDA receptor-dependent switching b..." refers background in this paper
...The basic mechanism of generation of population gamma rhythms by local neuronal circuits reveals an absolute dependence on the influence of fast spiking inhibitory interneurons at the level of principal cell somata (5, 6),with the frequency dependent on the magnitude and kinetics of gamma aminobutyric acid (GABAA) receptor-mediated synaptic events (7)....
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1,529 citations
"NMDA receptor-dependent switching b..." refers background in this paper
...For example, removal of entorhinal cortex in vivo produces a slower gamma rhythm (39), whose origins appear to be in area CA3 (40)....
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985 citations
"NMDA receptor-dependent switching b..." refers background in this paper
...For example, removal of entorhinal cortex in vivo produces a slower gamma rhythm (39), whose origins appear to be in area CA3 (40)....
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899 citations