NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation.
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"NOD2 stimulation induces autophagy ..." refers background in this paper
...During macroautophagy (hereafter referred to as autophagy), cytoplasmic material, including organelles, protein aggregates or bacteria, is sequestered into double membrane–coated autophagosomes that subsequently fuse with endosomes and lysosomes to form autolysosomes where lysosomal degradation can occu...
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6,244 citations
"NOD2 stimulation induces autophagy ..." refers background in this paper
...Phosphatidylethanolamine-conjugated LC3 (LC3-II) is localized in the inner and outer membranes of autophagosomes, and the population associated with the inner membrane is degraded after fusion of autophagosomes with lysosome...
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5,388 citations
"NOD2 stimulation induces autophagy ..." refers background in this paper
...NOD2 is distinguishable in that polymorphisms in the ligand recognition domain are associated with Crohn's diseas...
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4,838 citations
"NOD2 stimulation induces autophagy ..." refers background in this paper
...NOD2 is distinguishable in that polymorphisms in the ligand recognition domain are associated with Crohn's diseas...
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