Nutrient sensing and inflammation in metabolic diseases.
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...Because a highfat diet is needed in almost all experimental models to induce pathology, it is evident that dietary factors and nutrient sensing are cornerstones of these diseases.(113) Whereas genetic factors overall may play a minor role in the current epidemic of obesity, certain genetic factors might well offer explanations for a more progressive disease course in NAFLD....
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"Nutrient sensing and inflammation i..." refers background in this paper
...jpg" NDATA ITEM> ]> The integration of metabolism and immunity (or of nutrient- and pathogen-sensing pathways) can be traced back to an evolutionary need for survival, which resulted in the co-development of the organ systems and signalling pathways that mediate these two processe...
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"Nutrient sensing and inflammation i..." refers background in this paper
...This programme includes the upregulation of ER-resident chaperone proteins , which promote protein folding, and the production of components of the protein-degradation apparatus that assist in the re-establishment of ER homeostasi...
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