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Open AccessJournal ArticleDOI

O colágeno em fáscia transversal de pacientes com hérnia inguinal direta submetidos à videolaparoscopia

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TLDR
The direct inguinal hernia patients have less collagen in transversalis fascia either absolutely or relatively to other constitutional elements, stablishing that there are less collagenIn the hernia's wall.
Abstract
OBJETIVO: Analisar quanto a espessura, elementos constitutivos e quantificacao do colageno total amostras de fascias transversais de pacientes entre 20 e 60 anos de idade, com hernia inguinal direta, coletadas no momento da correcao videolaparoscopica, comparando-as com amostras do mesmo tecido, retiradas de cadaveres. METODOS: Biopsias de 23 pacientes e de 22 cadaveres foram analisadas e comparadas. Utilizaram-se as tecnicas de coloracao de Hematoxilina-Eosina e Picrosirius. As imagens captadas foram analisadas por tecnica videomorfometrica assistida por computador. RESULTADOS: Constatou-se uma espessura de fascia transversal nos controles, em media, de 4.5 milimetros. A espessura da fascia transversal dos pacientes com hernia foi, em media, 58 % menor (p< 0.001). Nao se evidenciou algum processo de degeneracao das fibras de colageno atribuivel a senilidade. O principal elemento constitutivo da fascia, nos dois grupos, foi o tecido conjuntivo denso, representando cerca de 75 % nos controles e sendo um terco menor nos pacientes (p< 0.001). A area media percentual de colageno no campo amostral dos pacientes encontrada foi metade da area dos controles (p< 0.001), resultando em uma menor quantidade de colageno na parede posterior herniada. CONCLUSAO: Os pacientes com hernia inguinal direta apresentam menor quantidade de colageno tanto absoluta quanto relativamente aos demais elementos constitutivos da fascia transversal.

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Collagen I and III in women with diastasis recti.

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Luciano Zogbi
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Collagen fibers in the rectus abdominis muscle of cadavers of different age

TL;DR: The amounts of types I and III collagen in the rectus abdominis muscle were significantly smaller in older subjects than in younger subjects, and immunohistochemical analysis confirmed this.
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Hiatal hernia and gastroesophageal reflux: Study of collagen in the phrenoesophageal ligament

TL;DR: The data indicate that the composition of POL for patients with GERD and HH includes less total, type-I, and type-III collagens than that of the POL of cadavers without HH, suggesting the quality of thePOL may be an etiological factor in the development of HH.
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Immunohistochemical analysis of collagen content and types in the rectus abdominis muscle of cadavers of different ages

TL;DR: In this article, the authors used immunohistochemical analysis to assess the collagen content and types in the rectus abdominis muscle of cadavers of different ages, and found that the amount of type I and type III collagen was higher in group A.
References
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Journal ArticleDOI

Comparison of Conventional Anterior Surgery and Laparoscopic Surgery for Inguinal-Hernia Repair

TL;DR: Patients with inguinal hernias who undergo laparoscopic repair recover more rapidly and have fewer recurrences than those who undergo open surgical repair.
Journal ArticleDOI

Increases in type III collagen gene expression and protein synthesis in patients with inguinal hernias.

TL;DR: This study represents the first attempt to define individuals with an abnormality in collagen production that may be specifically related to herniation, and suggests a constitutive and systemic increase in type III collagen synthesis may result in reduced collagen fibril assembly in the abdominal wall, eventually leading to the development of hernia.
Journal ArticleDOI

Inguinal hernia repair in adults