Oesophageal obstruction and ulceration caused by oral potassium therapy
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TLDR
A case is described of oesophageal ulceration and hold up following oral potassium therapy in a patient who had recently undergone mitral valve replacement.Abstract:
A case is described of oesophageal ulceration and hold up following oral potassium therapy. The patient had recently undergone mitral valve replacement.read more
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Controlled-Release Multiple-Units and Single-Unit Doses a Literature Review
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Pill-induced esophageal injury. Case reports and review of the medical literature
James Walter Kikendall,James Walter Kikendall,James Walter Kikendall,Arnold C. Friedman,Arnold C. Friedman,Arnold C. Friedman,Morakinyo Anthony Oyewole,Morakinyo Anthony Oyewole,Morakinyo Anthony Oyewole,David Fleischer,David Fleischer,David Fleischer,Lawrence F. Johnson,Lawrence F. Johnson,Lawrence F. Johnson +14 more
TL;DR: In this paper, the authors report four cases of esophageal injury associated with the ingestion of commonly prescribed tablets or capsules, and the history and clinical characteristics of these cases suggest that the medications failed to transit the esophagus and acted locally to produce esophagitis.
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Drug-induced oesophageal disorders: pathogenesis, incidence, prevention and management
TL;DR: The possibility of drug-related damage should be suspected in all cases of oesophagitis, chest pain and dysphagia and the treatment is supportive, although acid reduction is used frequently as an adjunct.
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Drug-induced dysphagia
B. Stoschus,H. D. Allescher +1 more
TL;DR: Dysphagia is a common clinical symptom in patients with reduced perception of the pharyngeal mucosa which leads to an subjective impairment of swallowing and can be caused in many different ways.
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Introduction of new therapeutic drugs in the United States and Great Britain: An international comparison
TL;DR: The pattern of introduction of new therapeutic drugs in the United States during the decade 1962 to 1971 has been compared with that in Great Britain and the drug lag was found to be most marked in cardiovascular, gastrointestinal, respiratory, diuretic, and antibacterial drugs.
References
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The critical role of chloride in the correction of hypokalemic alkalosis in man
TL;DR: It has been proposed that so long as hypochloremia persists, a disproportion between the quantity of sodium reabsorbed and the amount of penetrating anion available for reabsorption will maintain an accelerated rate of sodium-hydrogen and sodium-potassium exchange.
Journal ArticleDOI
Potassium-Induced Lesions of the Small Bowel: I. Clinical Aspects
TL;DR: Enteric-coated potassium chloride is responsible for a striking increase in ulcerative lesions of the small intestine; patients present with obstruction or signs of perforation, or both, and rarely with bleeding.
Journal ArticleDOI
The circumferential small-bowel ulcer: clinical aspects in 17 patients.
TL;DR: In 17 additional cases of circumferential small-bowel ulcer, thiazide potassium chloride therapy seems implicated in the causation of the lesion.
Journal ArticleDOI
Potassium-induced lesions of the small bowel. ii. pathology and pathogenesis.
TL;DR: The conclusion that an orally administered agent ulcerates the intestine by a topical, escharotic action is the natural one but the morphological and physiological evidence does not substantiate it.
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