Off-axis holography and micro-optics improve lab-on-a-chip imaging.
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TLDR
A pocket holographic slide enables the high-throughput screening of fluid samples by embedding micro-optics directly on a micro-channel to achieve off-axis interferometric imaging.Abstract:
A pocket holographic slide enables the high-throughput screening of fluid samples by embedding micro-optics directly on a micro-channel to achieve off-axis interferometric imaging. This holographic slide can be used to turn a conventional microscope into a phase-contrast imager or as a stand-alone compact imaging device by incorporating polymer lenses that are printed directly on-chip.read more
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Quantifying Embolism: Label-Free Volumetric Mapping of Thrombus Structure and Kinesis in a Microfluidic System with Optical Holography
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Single-pixel coherent diffraction imaging
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Synthetic optical holography for in-depth imaging of optical vortices in speckle patterns
A. Di Donato,M. Tamagnone,Luigino Criante,Luca Cavanini,Davide Mencarelli,Gianluca Ippoliti,Luca Pierantoni,Giuseppe Orlando,Antonio Morini,Marco Farina +9 more
TL;DR: In this paper, a novel approach based on a lensless Synthetic Optical Holography (SOH) that is aimed to recover the complex scattered field from buried surfaces at different wavelengths with sub-nanometric spectral resolution, without affecting the phase retrieval in depth.
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A Two-Stage Separation of Circulating Tumor Cells Based on Deterministic Lateral Displacement and Dielectrophoresis Techniques
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References
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Spatial filtering for zero-order and twin-image elimination in digital off-axis holography
TL;DR: Off-axis holograms recorded with a CCD camera are numerically reconstructed with a calculation of scalar diffraction in the Fresnel approximation and the zero order of diffraction and the twin image are digitally eliminated by means of filtering their associated spatial frequencies in the computed Fourier transform of the hologram.
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Digital in-line holography for biological applications
TL;DR: Digital in-line holography with numerical reconstruction has been developed into a new tool, specifically for biological applications, that routinely achieves both lateral and depth resolution, at least at the micron level, in three-dimensional imaging.
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Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications
Onur Mudanyali,Derek Tseng,Chulwoo Oh,Serhan O. Isikman,Ikbal Sencan,Waheb Bishara,Cetin Oztoprak,Sungkyu Seo,Bahar Khademhosseini,Aydogan Ozcan +9 more
TL;DR: This lensless incoherent holographic microscope has orders-of-magnitude improved light collection efficiency and is very robust to mechanical misalignments it may offer a cost-effective tool especially for telemedicine applications involving various global health problems in resource limited settings.
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High-throughput lensfree 3D tracking of human sperms reveals rare statistics of helical trajectories
TL;DR: A lensfree on-chip imaging technique that can track the three-dimensional trajectories of > 1,500 individual human sperms within an observation volume of approximately 8–17 mm3 and could in general be quite valuable for observing the statistical swimming patterns of various other microorganisms, leading to new insights in their 3D motion and the underlying biophysics.
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Optical imaging techniques for point-of-care diagnostics
TL;DR: A review of state-of-the-art optical imaging techniques that can have a significant impact on global health by facilitating effective and affordable POC diagnostics is presented in this article.