On a roll for new TRF targets
Citations
489 citations
Cites background from "On a roll for new TRF targets"
...This concept is nicely exemplified in studies of the TBP-related factors (TRFs) (for reviews, see: Jones, 2007; Müller et al., 2007; Reina and Hernandez, 2007; Torres-Padilla and Tora, 2007)....
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380 citations
193 citations
Cites background from "On a roll for new TRF targets"
...The other subunits of TFIID (the TBP-associated factors or TAFs) appear to interact with INR and DPEs....
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...Leurent C, Sanders S, Ruhlmann C, Mallouh V, Weil PA, Kirschner DB, Tora L, Schultz P: Mapping histone fold TAFs within yeast TFIID....
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...In higher eukaryotes, there are multiple genes encoding TBP-related factors (TRFs) and variant TAFs [1,7]....
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140 citations
Cites background from "On a roll for new TRF targets"
...which is essential for interaction with the TATA box (reviewed in [121-123, 144-146]....
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83 citations
References
119 citations
"On a roll for new TRF targets" refers background or methods in this paper
...TRF2 was discovered by analysis of ESTs by several groups and, accordingly, variously named TRF2 (Rabenstein et al. 1999; Teichmann et al. 1999), TRF (Maldonado 1999), TLP (Ohbayashi et al. 1999, 2001), TLF (Kaltenbach et al. 2000; Veenstra et al. 2000), or TBPrelated protein (TRP) (Moore et al.…...
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...Rather, it can inhibit TBP and TFIID-mediated transcription in such assays, probably in part by sequestering TFIIA (Moore et al. 1999; Teichmann et al. 1999; Nakadai et al. 2004)....
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...…cells contain two TFIIIB activities involved in transcription of distinct classes of pol III genes, one corresponding to yeast TFIIIB containing human Brf1 and TBP, and a second one in which Brf1 is replaced by another TFIIB-related factor called Brf2 (Teichmann et al. 1999; Schramm et al. 2000)....
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...Moreover, human cells contain two TFIIIB activities involved in transcription of distinct classes of pol III genes, one corresponding to yeast TFIIIB containing human Brf1 and TBP, and a second one in which Brf1 is replaced by another TFIIB-related factor called Brf2 (Teichmann et al. 1999; Schramm et al. 2000)....
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...Moreover, it cannot replace TBP for pol III transcription in extracts from human cells, at least for those genes that recruit the Brf1-containing TFIIIB activity (Teichmann et al. 1999)....
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119 citations
"On a roll for new TRF targets" refers background in this paper
...This provides a possible mechanism for earlier observations linking TRF2 with chromatin structure (Martianov et al. 2002; Kopytova et al. 2006)....
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...Extensive cytological analysis of these null mice revealed a defect in chromatin condensation in early spermatids, suggesting a function of TRF2 in chromatin organization, in particular in the formation of chromocenter structures (Martianov et al. 2002)....
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113 citations
"On a roll for new TRF targets" refers background in this paper
...Sequence alignments and phylogenetic analyses indicate that the TRF2s from a number of metazoans group together in a family that is more distantly related to TBP than TRF1 (Dantonel et al. 1999)....
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106 citations
104 citations
"On a roll for new TRF targets" refers background or result in this paper
...As a family, the TRF2s are less conserved than the TBPs: The TRF2 core domains are ∼40% identical to TBP core domains, but TRF2 core domains are 40%–45% identical among metazoans, whereas TBP core domains are 80% identical from yeast to human (Dantonel et al. 2000)....
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...This is consistent with studies in nematode, fly, fish, and frog, where inactivation of TRF2 results in a block in embryonic development and lethality (Dantonel et al. 2000; Kaltenbach et al. 2000; Veenstra et al. 2000; Bartfai et al. 2004; Kopytova et al. 2006)....
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