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Journal ArticleDOI

Online measurement of dissolved oxygen in shake flask to elucidate its role on caffeine degradation by Pseudomonas sp.

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TLDR
Higher DO in the medium is required for efficient conversion of caffeine to theobromine which is in agreement that the reaction is oxidative demethylation which will be useful in shaking flask studies and scaling up processes.
Abstract
Caffeine is a plant alkaloid present in the large ratio over other emerging pollutants and it causes serious health effects on overdosage. Microbial degradation of caffeine produces metabolites tha...

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Citations
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Self-directing optimization for enhanced caffeine degradation in synthetic coffee wastewater using induced cells of Pseudomonas sp.: Bioreactor studies

TL;DR: In this paper, a regression model was developed to predict the caffeine degradation rate with oxygen mass transfer coefficient (kLa) and initial biomass concentration, and the optimal conditions of initial biomass and kLa were 0.23g/L and 64.26h−1 respectively.
Journal ArticleDOI

Monitoring of Oxygen, pH, CO 2 , and Biomass in Smart Single‐Use Shake Flasks

TL;DR: In this article , optical sensors are employed in single-use shake flasks to measure oxygen, carbon dioxide, pH, and biomass, and optical sensors can also be used to measure carbon dioxide and carbon dioxide.
Journal ArticleDOI

Optimization by uniform design U8(83) approach for enhanced caffeine degradation in synthetic wastewater in bioreactor

TL;DR: This is the first‐ever bioreactor study showing highest caffeine degradation rate in synthetic coffee wastewater with limited experimental runs.
References
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Journal ArticleDOI

Optimization of production of caffeine demethylase by Pseudomonas sp. in a bioreactor

TL;DR: Different metabolite formation at different agitation and aeration rates can be used as a strategy for recovery of pharmaceutically important metabolites from caffeine by manipulation of conditions in a bacterial culture.
Journal ArticleDOI

Response Surface Optimization for Decaffeination and Theophylline Production by Fusarium solani

TL;DR: Results show that a viable and sustainable process can be developed for the detoxification of caffeine along with the recovery of theophylline, a commercially important chemical.
Journal Article

Application of response surface methodology for optimising caffeine-degrading parameters by Leifsonia sp. strain SIU.

TL;DR: Second order polynomial regression model accurately showed interpretation of experimental data with an R2 value of 0.9989 and F values of 88.77, in order to get the most superior degradation conditions.
Journal ArticleDOI

Study on the interaction and antioxidant activity of theophylline and theobromine with SOD by spectra and calculation

TL;DR: The results indicate that the complex formation of TP-S OD and TB-SOD can maintain their respective antioxidant effects without changes in the activity of SOD.
Journal ArticleDOI

How induced cells of Pseudomonas sp. increase the degradation of caffeine

TL;DR: This is the first report on a strain that can degrade high concentrations of caffeine at the maximum rate of 0.385 g/l per hour, and suggests that the strain can be used in developing a biological process for the degradation of caffeine.