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Operational classification of seizure types by the International League Against Epilepsy: position paper of the ILAE Commission for Classification and Terminology

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TLDR
The International League Against Epilepsy presents a revised operational classification of seizure types to recognize that some seizure types can have either a focal or generalized onset, to allow classification when the onset is unobserved, to include some missing seizure types, and to adopt more transparent names.
Abstract
The International League Against Epilepsy (ILAE) presents a revised operational classification of seizure types. The purpose of such a revision is to recognize that some seizure types can have either a focal or generalized onset, to allow classification when the onset is unobserved, to include some missing seizure types, and to adopt more transparent names. Because current knowledge is insufficient to form a scientifically based classification, the 2017 Classification is operational (practical) and based on the 1981 Classification, extended in 2010. Changes include the following: (1) "partial" becomes "focal"; (2) awareness is used as a classifier of focal seizures; (3) the terms dyscognitive, simple partial, complex partial, psychic, and secondarily generalized are eliminated; (4) new focal seizure types include automatisms, behavior arrest, hyperkinetic, autonomic, cognitive, and emotional; (5) atonic, clonic, epileptic spasms, myoclonic, and tonic seizures can be of either focal or generalized onset; (6) focal to bilateral tonic-clonic seizure replaces secondarily generalized seizure; (7) new generalized seizure types are absence with eyelid myoclonia, myoclonic absence, myoclonic-atonic, myoclonic-tonic-clonic; and (8) seizures of unknown onset may have features that can still be classified. The new classification does not represent a fundamental change, but allows greater flexibility and transparency in naming seizure types.

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Epilepsy in adults

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The Human Phenotype Ontology in 2021

Sebastian Köhler, +56 more
TL;DR: Recent major extensions of the Human Phenotype Ontology for neurology, nephrology, immunology, pulmonology, newborn screening, and other areas are presented and new efforts to harmonize computational definitions of phenotypic abnormalities across the HPO and multiple phenotype ontologies used for animal models of disease are presented.
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Global, regional, and national burden of epilepsy, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016

Ettore Beghi, +108 more
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TL;DR: Despite the decrease in the disease burden from 1990 to 2016, epilepsy is still an important cause of disability and mortality, and was similar among SDI quintiles.
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The Epidemiology of Epilepsy.

TL;DR: The overall prognosis of epilepsy is favorable in the majority of patients when measured by seizure freedom, and reports from low/middle-income countries (LMIC; where patients with epilepsy are largely untreated) give prevalence and remission rates that overlap those of HICs.
References
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Journal ArticleDOI

A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of the ILAE Task Force on Classification and Terminology.

TL;DR: A diagnostic scheme that makes use of standardized terminology and concepts to describe individual patients is proposed, and a variety of approaches to classification are possible, and some are presented here by way of example only.

A Classification of

TL;DR: This work provides a classification of the set of multicast protocols using the user requirements, and illustrates it with several example protocols chosen to cover the range of features described.
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