Optimal pain management for patients with cancer in the modern era.
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TLDR
The authors provide a framework for safely and effectively managing cancer‐related pain by summarizing the evidence for the importance of controlling pain, the barriers to adequate pain management, strategies to assess and manage cancer-related pain, how to manage pain in patients at risk of substance use disorder, and considerations when managing pain in a survivorship population.Abstract:
Pain is a common symptom among patients with cancer. Adequate pain assessment and management are critical to improve the quality of life and health outcomes in this population. In this review, the authors provide a framework for safely and effectively managing cancer-related pain by summarizing the evidence for the importance of controlling pain, the barriers to adequate pain management, strategies to assess and manage cancer-related pain, how to manage pain in patients at risk of substance use disorder, and considerations when managing pain in a survivorship population. CA Cancer J Clin 2018;68:182-196. © 2018 American Cancer Society.read more
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Cancer Pain and Quality of Life.
TL;DR: Cancer pain was associated with significant distress and interference with life activities and occurred frequently or constantly for many study patients.
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Intranasal delivery of Naloxone-loaded solid lipid nanoparticles as a promising simple and non-invasive approach for the management of opioid overdose.
Nazeer Hasan,Nazeer Hasan,Nazeer Hasan,Mohammad Imran,Prashant Kesharwani,Kushagra Khanna,Kushagra Khanna,Ritu Karwasra,Nitin Sharma,Sonalika Rawat,Deeksha Sharma,Farhan Jalees Ahmad,Gaurav K. Jain,Aseem Bhatnagar,Sushama Talegaonkar +14 more
TL;DR: In this paper, the authors developed intranasal solid-lipid nanoparticles in which naloxone was incorporated for the higher brain disposition of Noxone with superior therapeutic effects for the reversal of toxicity of opioid overdose.
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Careful Breakthrough Cancer Pain Treatment through Rapid-Onset Transmucosal Fentanyl Improves the Quality of Life in Cancer Patients: Results from the BEST Multicenter Study
Arturo Cuomo,Marco Cascella,Cira Antonietta Forte,Sabrina Bimonte,Gennaro Esposito,Stefano De Santis,Luigi Cavanna,Flavio Fusco,Mario Dauri,Silvia Natoli,Marco Maltoni,Alessandro Morabito,Rocco Domenico Mediati,Vito Lorusso,Sandro Barni,Giampiero Porzio,Sebastiano Mercadante,Anna Crispo +17 more
TL;DR: This prospective investigation by an Italian expert group has confirmed that careful management of BTcP induces a paramount improvement on the HRQoL in patients with cancer pain.
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Long-Term Opioid Therapy in Older Cancer Survivors: A Retrospective Cohort Study
TL;DR: To examine the rates and predictors of long‐term opioid therapy in older cancer survivors, a large number of patients diagnosed with cancer in the 1980s and 90s received treatment with morphine or heroin.
References
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TL;DR: An issue concerning the criteria for tic disorders is highlighted, and how this might affect classification of dyskinesias in psychotic spectrum disorders.
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TL;DR: The role of opioids in the treatment of chronic pain is influenced by the fact that these potent analgesics are associated with a significant number of side effects and complications, and these phenomena are the focus of this review.
Journal ArticleDOI
Prevalence of pain in patients with cancer: a systematic review of the past 40 years
M.H.J. van den Beuken-van Everdingen,J.M. de Rijke,Alphons G.H. Kessels,Harry C. Schouten,M. van Kleef,Jacob Patijn +5 more
TL;DR: Pooled prevalence of pain was >50% in all cancer types with the highest prevalence in head/neck cancer patients (70%; 95% CI 51% to 88%).
Journal ArticleDOI
Cannabinoids for Medical Use: A Systematic Review and Meta-analysis.
Penny Whiting,Penny Whiting,Robert Wolff,Sohan Deshpande,Marcello Di Nisio,Steven Duffy,Adrian V. Hernandez,Adrian V. Hernandez,J. Christiaan Keurentjes,Shona H. Lang,Kate Misso,Steve Ryder,Simone Schmidlkofer,Marie Westwood,Jos Kleijnen +14 more
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