Optimization of ultrasound-assisted extraction (UAE) of flavonoids compounds (FC) from hawthorn seed (HS)
TL;DR: The ultrasound-assisted extraction (UAE) of FC from HS was investigated and the optimum levels of these significant parameters were determined using response surface methodology (RSM), which revealed these as follows.
About: This article is published in Ultrasonics Sonochemistry.The article was published on 2012-05-01 and is currently open access. It has received 144 citations till now. The article focuses on the topics: Extraction (chemistry).
Citations
More filters
TL;DR: The most commonly used methods for their extraction are the conventional liquid-liquid or solid-liquid extraction and the advanced methods include pressurized liquid extraction, subcritical and supercritical extractions, and microwave-and ultrasound-assisted extractions.
Abstract: Natural bioactive compounds include a broad diversity of structures and functionalities that provide an excellent pool of molecules for the production of nutraceuticals, functional foods, and food additives. Some of those compounds can be found in nature at high concentration such as polyphenols but others can only be found at very low levels, so that massive harvesting is needed to obtain sufficient amounts, and their structural diversity and complexity make chemical synthesis unprofitable. The inherent difficulties in screening and producing these compounds have led to the development of advanced technologies. The commonly used methods for their extraction are the conventional liquid–liquid or solid–liquid extraction and the advanced include pressurized-liquid extraction, subcritical and supercritical extractions, and microwave- and ultrasound-assisted extractions. In addition, these extraction techniques have been improved with previous steps (enzyme-and instant controlled pressure drop-assisted extractions) which help to release the compounds from the matrix. These technologies could provide in the next few years an innovative approach to increase the production of specific compounds for use as nutraceuticals or as ingredients in the design of functional foods.
510 citations
TL;DR: The factor affecting the UAE of bioactive compounds from fruit and vegetable by-products is summarized and RSM with numerical optimization is commonly used for optimization of UAE.
338 citations
TL;DR: The predicted values were in correlation with experimental values with 95% confidence level, under the determined optimal conditions, indicating the significance of selected method for USLE of phytochemicals from SCG.
224 citations
Cites background from "Optimization of ultrasound-assisted..."
...UAE was found to be the most efficient technique among the above mentioned extraction technique....
[...]
...The same tendency was resulted in polysaccharides extraction from Acanthopanax senticosus [32] and Boletus edulis mycelia [33] using UAE....
[...]
...Microwave-assisted extraction (MAE) [8], ultrasound-assisted extraction (UAE) [9], accelerated solvent extraction (ASE) [10] and supercritical fluid extraction (SFE) [11] are some trending techniques for the recovery of phenolic compounds from waste materials and other sources....
[...]
TL;DR: This review will discuss the different methods available for flavonoid extraction from natural sources and the main parameters involved, presenting in each of them their advantages and disadvantages, trying to offer a broader scope in the understanding of flavonoids extraction from different plant matrices.
Abstract: Flavonoids are one of the main groups of polyphenols found in natural products. Traditional flavonoid extraction techniques are being replaced by advanced techniques to reduce energy and solvent consumption, increase efficiency and selectivity, to meet increased market demand and environmental regulations. Advanced technologies, such as microwaves, ultrasound, pressurized liquids, supercritical fluids, and electric fields, are alternatives currently being used. These modern techniques are generally faster, more environmentally friendly, and with higher automation levels compared to conventional extraction techniques. This review will discuss the different methods available for flavonoid extraction from natural sources and the main parameters involved (temperature, solvent, sample quantity, extraction time, among others). Recent trends and their industrial importance are also discussed in detail, providing insight into their potential. Thus, this paper seeks to review the innovations of compound extraction techniques, presenting in each of them their advantages and disadvantages, trying to offer a broader scope in the understanding of flavonoid extraction from different plant matrices.
183 citations
TL;DR: Results indicate that an important quantity of bioactive compounds can be extracted from spruce wood bark by ultrasound assisted extraction technology.
178 citations
References
More filters
Book•
29 Aug 1995TL;DR: Using a practical approach, this book discusses two-level factorial and fractional factorial designs, several aspects of empirical modeling with regression techniques, focusing on response surface methodology, mixture experiments and robust design techniques.
Abstract: From the Publisher:
Using a practical approach, it discusses two-level factorial and fractional factorial designs, several aspects of empirical modeling with regression techniques, focusing on response surface methodology, mixture experiments and robust design techniques. Features numerous authentic application examples and problems. Illustrates how computers can be a useful aid in problem solving. Includes a disk containing computer programs for a response surface methodology simulation exercise and concerning mixtures.
10,104 citations
TL;DR: Flavonoids in regularly consumed foods may reduce the risk of death from coronary heart disease in elderly men and showed an inverse relation with incidence of myocardial infarction.
4,440 citations
TL;DR: In this article, a critical review was conducted to introduce and compare the conventional Soxhlet extraction and the new alternative methods used for the extraction of nutraceuticals from plants, and the practical issues of each extraction method were discussed.
Abstract: Various novel techniques including ultrasound-assisted extraction, microwave-assisted extraction, supercritical fluid extraction, and accelerated solvent extraction have been developed for the extraction of nutraceuticals from plants in order to shorten the extraction time, decrease the solvent consumption, increase the extraction yield, and enhance the quality of extracts. A critical review was conducted to introduce and compare the conventional Soxhlet extraction and the new alternative methods used for the extraction of nutraceuticals from plants. The practical issues of each extraction method were discussed. Potential uses of those methods for the extraction of nutraceuticals from plant materials was finally summarized.
1,770 citations
TL;DR: All with an interest in tumours will find something to stimulate them in this book but even these items are to some extent outweighed by the insight given into the thoughts and policies of this fascinating country.
Abstract: It is one of the anomalies of political history that the international medical world has, until recently, been better informed about cancer patterns and cancer research in tropical Africa than in China. Following the overthrow of the 'Gang of Four' a team of US oncologists travelled widely through that vast country, and this book is a record of what they saw. It gives a detailed account of cancer epidemiology, research, diagnosis, and treatment, and of the medico-political background. Most people are familiar with what seems to western eyes to be a curious combination of traditional medicine (acupuncture and herbal therapy) and of high technology, particularly in the field of surgery. Fewer may be aware of the interesting epidemiological studies which have shown high incidence areas of oesophageal, nasopharyngeal, and hepatic carcinoma; of the geographical association of some of these tumours with a high incidence in domestic animals; or of the diagnosis of precancerous oesophageal lesions by cytology obtained by barefoot doctors. All with an interest in tumours will find something to stimulate them in this book but even these items are to some extent outweighed by the insight given into the thoughts and policies of this fascinating country.
1,210 citations
TL;DR: In this article, a face-centered cubic design (FCD) was used to investigate the effects of solvent composition (%), extraction temperature (°C) and time (min) on the response, total antioxidant activity (TAA).
720 citations