OPTN/SRTR 2016 Annual Data Report: Kidney.
Allyson Hart,Jodi M. Smith,Melissa Skeans,Sally K. Gustafson,Amber R. Wilk,A. Robinson,J. L. Wainright,C. R. Haynes,Jon J. Snyder,Bertram L. Kasiske,Ajay K. Israni +10 more
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TLDR
Transplant rates that had changed dramatically for some groups after implementation of the new kidney allocation system in 2014 are stabilizing, allowing for evaluation of new steady states and trends, and a decline in the proportion of living donor transplants is of concern for pediatric recipients.About:
This article is published in American Journal of Transplantation.The article was published on 2018-01-01 and is currently open access. It has received 422 citations till now. The article focuses on the topics: Kidney transplantation & Transplantation.read more
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Journal ArticleDOI
Solid organ transplantation in the 21 st century
TL;DR: The field of SOT faces new barriers, most importantly the expanding demand for SOT that is outpacing the current supply, and allocation protocols have been developed in an attempt to address these concerns.
Journal ArticleDOI
Post-transplant diabetes mellitus in patients with solid organ transplants
TL;DR: This Review presents the current knowledge on post-transplant diabetes mellitus in patients receiving kidney, heart, liver and lung transplants and outlines the pathogenesis, diagnosis, treatment and prevention of PTDM.
Journal ArticleDOI
Trends in the Causes of Death among Kidney Transplant Recipients in the United States (1996-2014).
Ahmed A. Awan,Jingbo Niu,Jenny Szu-Chin Pan,Jenny Szu-Chin Pan,Kevin F. Erickson,Sreedhar Mandayam,Sreedhar Mandayam,Wolfgang C. Winkelmayer,Sankar D. Navaneethan,Sankar D. Navaneethan,Venkat Ramanathan,Venkat Ramanathan +11 more
TL;DR: Despite the downtrend in mortality over the last 2 decades, a significant percentage of KTRs die in 10-years with a functioning graft, and cardiovascular mortality remains the leading cause of death.
Journal ArticleDOI
Dissociation of C-Reactive Protein Localizes and Amplifies Inflammation: Evidence for a Direct Biological Role of C-Reactive Protein and Its Conformational Changes.
James D. McFadyen,Jurij Kiefer,David Braig,Julia Loseff-Silver,Lawrence A. Potempa,Steffen U. Eisenhardt,Karlheinz Peter,Karlheinz Peter,Karlheinz Peter +8 more
TL;DR: Understanding the “activation process” of CRP will likely allow the development of novel anti-inflammatory drugs, thereby providing potential new immunomodulatory therapeutics in a broad range of inflammatory diseases.
Journal ArticleDOI
Eplet Mismatch Load and De Novo Occurrence of Donor-Specific Anti-HLA Antibodies, Rejection, and Graft Failure after Kidney Transplantation: An Observational Cohort Study.
Aleksandar Senev,Maarten Coemans,Evelyne Lerut,Vicky Van Sandt,Johan Kerkhofs,Liesbeth Daniels,Marleen Vanden Driessche,Veerle Compernolle,Ben Sprangers,Elisabet Van Loon,Jasper Callemeyn,Frans H.J. Claas,Anat R. Tambur,Geert Verbeke,Dirk Kuypers,Marie-Paule Emonds,Maarten Naesens +16 more
TL;DR: Eplet mismatches in HLA-DQ confer substantial risk for de novo DSA formation, graft rejection, and graft failure after kidney transplantation and are suggested to be used to guide personalized post-transplant immunosuppression.
Related Papers (5)
KDIGO clinical practice guideline for the care of kidney transplant recipients: a summary
Bertram L. Kasiske,Martin Zeier,Jeremy R. Chapman,Jonathan C. Craig,Henrik Ekberg,Catherine A. Garvey,Michael Green,Vivekanand Jha,Michelle A. Josephson,Bryce A. Kiberd,Henri Kreis,Ruth A. McDonald,John M. Newmann,Gregorio T. Obrador,Flavio Vincenti,Michael Cheung,Amy Earley,Gowri Raman,Samuel A Abariga,Martin Wagner,Ethan M Balk +20 more