Oral status in patients with early rheumatoid arthritis: a prospective, case–control study
Björn Wolff,Timo Berger,Cornelia Frese,Regina Max,Norbert Blank,Hanns-Martin Lorenz,Diana Wolff +6 more
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Increased loss of periodontal attachment and alveolar bone can be detected in patients with ERA, therefore it is proposed that the consulting rheumatologists inform the patients that they have a higher risk ofperiodontal disease.Abstract:
Objective. Patients with RA suffer from a higher risk of periodontal attachment loss and increased oral inflammation. We hypothesize that there are pathogenetic and immunological interactions between these diseases that go beyond impaired manual dexterity accompanying advanced RA. The primary objective of the present study was to determine whether a loss of alveolar bone can be detected in RA patients during the early course of the disease. Methods. In this cross-sectional, epidemiological casecontrol study, 22 patients with early RA (ERA) were compared with 22 matched healthy controls. Oral and periodontal status, clinical activity, and sociodemographic parameters were determined. Oral microbiota were analysed using real-time quantitative PCR specific for leading oral pathogens. Results. More advanced forms of periodontitis were found in ERA patients compared with controls. ERA patients had a greater number of missing teeth [ERA 5.7 (S.D. 5.0), controls 1.9 (S.D. 1.0), P = 0.002], deeper periodontal pockets [clinical attachment level: ERA 3.4 (S.D. 0.5 mm), controls 2.7 (S.D. 0.3 mm), P < 0.000], and greater bleeding on probing [ERA 18.6% (S.D. 9.0%), controls 10.5% (S.D. 5.1%), P = 0.001] despite comparable oral hygiene. Tannerella forsythia (6.77-fold, P = 0.033) subgingivally and Streptococcus anginosus (3.56-fold, P = 0.028) supragingivally were the characteristic pathogens in ERA. Conclusion. Increased loss of periodontal attachment and alveolar bone can be detected in patients with ERA, therefore we propose that the consulting rheumatologists inform the patients that they have a higher risk of periodontal disease. It would be beneficial if these patients were referred directly for intensive dental care.read more
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Link between rheumatoid arthritis and chronic periodontitis
TL;DR: The current knowledge about the link between both diseases is reviewed, focusing on its clinical implications and will periodontal treatment become a part of standard therapy for rheumatoid arthritis.
Dental conditions in rheumatic diseases.
Jorge Antonio Esquivel Valerio,Mario Alberto Garza Elizondo,Jacqueline Rodríguez Amado,Myriam Angélica De La Garza-Ramos +3 more
TL;DR: The clinical presentations of rheumatic diseases, such as scleroderma, rheumatoid arthritis, Sjogren's syndrome, Systemic lupus erythematosus and others that present specific oral manifestations are described.
Mise en place d'une activité de transplantation de microbiote fécal dans un centre hospitalier universitaire et suivi des patients traités
TL;DR: In this paper, le transplantation de microbiote fecal (TMF) is described as a process of remplacer la flore desequilibree d a sujet malade par une flore qualifiee de saine d'un donneur de selles volontaire.
Journal ArticleDOI
Importancia del manejo interdisciplinario del paciente con enfermedad periodontal y/o artritis reumatoide
TL;DR: In this paper, a búsqueda bibliográfica con 5 años de antecedentes in la base of datos NCBI (National Center for Biotechnology Information), usando las palabras clave: enfermedad periodontal, artritis reumatoide, citrulinación, disbiosis oral and porphyromonas gingivalis, seleccionándose 52 artículos, se realiza la lectura crítica de ellos and la
Dissertation
Studies on the relationship between periodontitis and rheumatoid arthritis
TL;DR: The severity of periodontitis in relation to ACPA/RF status, immunological parameters associated with RA, and the presence of subgingival P. gingivalis DNA in patients with established RA was investigated.
References
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