Oral status in patients with early rheumatoid arthritis: a prospective, case–control study
Björn Wolff,Timo Berger,Cornelia Frese,Regina Max,Norbert Blank,Hanns-Martin Lorenz,Diana Wolff +6 more
Reads0
Chats0
TLDR
Increased loss of periodontal attachment and alveolar bone can be detected in patients with ERA, therefore it is proposed that the consulting rheumatologists inform the patients that they have a higher risk ofperiodontal disease.Abstract:
Objective. Patients with RA suffer from a higher risk of periodontal attachment loss and increased oral inflammation. We hypothesize that there are pathogenetic and immunological interactions between these diseases that go beyond impaired manual dexterity accompanying advanced RA. The primary objective of the present study was to determine whether a loss of alveolar bone can be detected in RA patients during the early course of the disease. Methods. In this cross-sectional, epidemiological casecontrol study, 22 patients with early RA (ERA) were compared with 22 matched healthy controls. Oral and periodontal status, clinical activity, and sociodemographic parameters were determined. Oral microbiota were analysed using real-time quantitative PCR specific for leading oral pathogens. Results. More advanced forms of periodontitis were found in ERA patients compared with controls. ERA patients had a greater number of missing teeth [ERA 5.7 (S.D. 5.0), controls 1.9 (S.D. 1.0), P = 0.002], deeper periodontal pockets [clinical attachment level: ERA 3.4 (S.D. 0.5 mm), controls 2.7 (S.D. 0.3 mm), P < 0.000], and greater bleeding on probing [ERA 18.6% (S.D. 9.0%), controls 10.5% (S.D. 5.1%), P = 0.001] despite comparable oral hygiene. Tannerella forsythia (6.77-fold, P = 0.033) subgingivally and Streptococcus anginosus (3.56-fold, P = 0.028) supragingivally were the characteristic pathogens in ERA. Conclusion. Increased loss of periodontal attachment and alveolar bone can be detected in patients with ERA, therefore we propose that the consulting rheumatologists inform the patients that they have a higher risk of periodontal disease. It would be beneficial if these patients were referred directly for intensive dental care.read more
Citations
More filters
Journal ArticleDOI
Porphyromonas Gingivalis - A Periodontal Pathogen with Potential Role in Rheumatoid Arthritis and its Association with Anti-CCP and Anti-MCV Antibodies Positivity
P. Selimov,Elena Firkova,L Damjanovska,Ginka Delcheva,Teodora Stankova,K. Stefanova,Ana Maneva,Anastas Batalov +7 more
TL;DR: PG was present more frequently in RA patients and there was a statistically significant association with anti CCP and anti MCV antibodies.
Journal ArticleDOI
Effet du traitement parodontal chez des patients atteints de polyarthrite rhumatoïde : essai clinique randomisé ESPERA
Paul Monsarrat,Paul Monsarrat,Claire Willmann,Arnaud Constantin,Cathy Nabet,Gabriel Fernandez de Grado,Michel Sixou,Alain Cantagrel,Thomas Barnetche,Nadia Mehsen-Cetre,Thierry Schaeverbeke,Elise Arrivé,Jean-Noel Vergnes,Jean-Noel Vergnes,Groupe Espera +14 more
TL;DR: Bien qu’aucun effet du traitement parodontal sur les parametres of the polyarthrite rhumatoide n’ait ete identifie, cet essai fournit des donnees importantes pour recommander les soinsParodontaux chez les patients atteints de PR.
Journal Article
Sustained Remission of a Seronegative Rheumatoid Arthritis after Dental Treatment: A Case Report
TL;DR: A case of sustained clinical remission of an anti-cyclic citrunillated (anti-CCP) peptide antibody negative early RA after dental treatment of oral infectious foci is reported.
Journal ArticleDOI
The Effectiveness of Waist-Shaped and Straight-Shaped Interdental Brushes in Cleaning Implant Overdenture Attachments: A Self-Controlled Clinical Trial
TL;DR: The waist-shaped interdental brushes were significantly more efficient in plaque removal than the straight-shaped ones, especially at the line-angle sites, and the post-cleaning mPLI scores were lower in the WIB group than in the SIB group.
Journal ArticleDOI
Zusammenhänge zwischen Parodontitis und rheumatischen Erkrankungen am Beispiel der rheumatoiden Arthritis
TL;DR: Wechselwirkungen mit anderen Medikamente sollten deshalb bei RA-Patienten, die zahnmedizinisch behandelt werden müssen, beachtet werde.
References
More filters
Journal ArticleDOI
2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative.
Daniel Aletaha,Tuhina Neogi,Alan J. Silman,Julia Funovits,David T. Felson,Clifton O. Bingham,Neal S. Birnbaum,Gerd Burmester,Vivian P. Bykerk,Marc D. Cohen,Bernard Combe,Karen H. Costenbader,Maxime Dougados,Paul Emery,Gianfranco Ferraccioli,Johanna M. W. Hazes,Kathryn Hobbs,Tom W J Huizinga,Arthur Kavanaugh,Jonathan Kay,Tore K Kvien,Timothy J. Laing,Philip J. Mease,Henri A Ménard,Larry W. Moreland,Raymond L. Naden,Theodore Pincus,Josef S Smolen,Ewa Stanislawska-Biernat,Deborah P M Symmons,Paul P. Tak,Katherine S. Upchurch,Jiří Vencovský,Frederick Wolfe,Gillian A. Hawker +34 more
TL;DR: This new classification system redefines the current paradigm of RA by focusing on features at earlier stages of disease that are associated with persistent and/or erosive disease, rather than defining the disease by its late-stage features.
Journal ArticleDOI
Development of a Classification System for Periodontal Diseases and Conditions
TL;DR: How the new classification for periodontal diseases and conditions presented in this volume differs from the classification system developed at the 1989 World Workshop in Clinical Periodontics is summarized.
Journal ArticleDOI
Microbial complexes in subgingival plaque
TL;DR: The purpose of the present investigation was to attempt to define communities using data from large numbers of plaque samples and different clustering and ordination techniques, which related strikingly to clinical measures of periodontal disease particularly pocket depth and bleeding on probing.
Journal Article
Problems and proposals for recording gingivitis and plaque.
TL;DR: The origin of indices for recording gingivitis and plaque is reviewed and the use of the site prevalence of a single finding is suggested, which could be used as a clinically relevant parameter for oral hygiene and gingival inflammation.
Journal ArticleDOI
The plaque control record
TL;DR: Examination systems for oral hygiene status use either selected teeth or the highest score for a group of teeth within a segment as the basis for their scores, which are of limited value for the clinician treating an individual patient.
Related Papers (5)
Periodontitis and Porphyromonas gingivalis in patients with rheumatoid arthritis.
Ted R. Mikuls,Jeffrey B. Payne,Fang Yu,Geoffrey M. Thiele,Richard J. Reynolds,Grant W. Cannon,Jeffrey Markt,David McGowan,Gail S. Kerr,Robert S. Redman,Andreas M. Reimold,Garth R. Griffiths,Mark W. Beatty,Shawneen M. Gonzalez,Debra A. Bergman,Bartlett C. Hamilton,Alan R Erickson,Jeremy Sokolove,William H. Robinson,Clay Walker,Fatiha Chandad,James R. O'Dell +21 more