Journal ArticleDOI
Organ printing: from bioprinter to organ biofabrication line
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This paper presents recent progress and challenges in the development of the essential components of an organ biofabrication line.About:
This article is published in Current Opinion in Biotechnology.The article was published on 2011-10-01. It has received 312 citations till now. The article focuses on the topics: Biofabrication.read more
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3D bioprinting of tissues and organs
Sean V. Murphy,Anthony Atala +1 more
TL;DR: 3D bioprinting is being applied to regenerative medicine to address the need for tissues and organs suitable for transplantation and developing high-throughput 3D-bioprinted tissue models for research, drug discovery and toxicology.
Journal ArticleDOI
Polymers for 3D Printing and Customized Additive Manufacturing
TL;DR: Polymers are by far the most utilized class of materials for AM and their design, additives, and processing parameters as they relate to enhancing build speed and improving accuracy, functionality, surface finish, stability, mechanical properties, and porosity are addressed.
Journal ArticleDOI
Current advances and future perspectives in extrusion-based bioprinting.
TL;DR: This paper, presenting a first-time comprehensive review of EBB, discusses the current advancements in EBB technology and highlights future directions to transform the technology to generate viable end products for tissue engineering and regenerative medicine.
Organ Printing: Tissue Spheroids as Building Blocks
Vladimir Mironov,Jing Zhang,Carmine Gentile,K Brakke,Thomas C. Trusk,Karoly Jakab,Gabor Forgacs,Vladimirs Kasjanovs,Richard P. Visconti,Roger R. Markwald +9 more
TL;DR: Organ printing can be defined as layer-by-layer additive robotic biofabrication of three-dimensional functional living macrotissues and organ constructs using tissue spheroids as building blocks.
Journal ArticleDOI
Additive manufacturing of tissues and organs
Ferry P.W. Melchels,Ferry P.W. Melchels,Marco Domingos,Travis J. Klein,Jos Malda,Jos Malda,Paulo Jorge Da Silva Bartolo,Dietmar W. Hutmacher,Dietmar W. Hutmacher +8 more
TL;DR: In this paper, the authors discuss the rationale for engineering tissues and organs by combining computer-aided design with additive manufacturing technologies that encompass the simultaneous deposition of cells and materials, particularly with respect to limitations due to the lack of suitable polymers and requirements to move the current concepts to practical application.
References
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Foundations for engineering biology
TL;DR: Vibrant, open research communities and strategic leadership are necessary to ensure that the development and application of biological technologies remains overwhelmingly constructive.
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Organ printing: computer-aided jet-based 3D tissue engineering
TL;DR: Combination of an engineering approach with the developmental biology concept of embryonic tissue fluidity enables the creation of a new rapid prototyping 3D organ printing technology, which will dramatically accelerate and optimize tissue and organ assembly.
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Scaffold-free vascular tissue engineering using bioprinting.
TL;DR: A fully biological self-assembly approach, which is implemented through a rapid prototyping bioprinting method for scaffold-free small diameter vascular reconstruction and has the ability to engineer vessels of distinct shapes and hierarchical trees that combine tubes of distinct diameters.
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The second wave of synthetic biology: from modules to systems
TL;DR: To view cells as true 'programmable' entities, it is now essential to develop effective strategies for assembling devices and modules into intricate, customizable larger scale systems.
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Recent advances in three-dimensional multicellular spheroid culture for biomedical research
Ruei-Zhen Lin,Hwan-You Chang +1 more
TL;DR: The current understanding of multicellular spheroid formation mechanisms, their biomedical applications, and recent advances in sp heroid culture, manipulation, and analysis techniques are reviewed.