Oriented immobilization of antibodies onto sensing platforms- A critical review
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TLDR
This review provides more insights into the fabrication of high-efficiency immunosensor, and special attention has been devoted to the well-orientation of full-length IgGs onto the sensing platform.About:
This article is published in Analytica Chimica Acta.The article was published on 2022-01-02 and is currently open access. It has received 51 citations till now. The article focuses on the topics: Chemistry & Covalent bond.read more
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Magnetic Nanoparticles: Current Advances in Nanomedicine, Drug Delivery and MRI
TL;DR: Superparamagnetic iron oxide nanoparticles (SPIONs) are established at the core of drug-delivery systems and could act as efficient agents for MFH (magnetic fluid hyperthermia).
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Detection of Low Density Lipoprotein-Comparison of Electrochemical Immuno- and Aptasensor.
TL;DR: In this article, the parameters characterizing the electrochemical immuno-and aptasensor for detection of LDL have been compared for the first time, and the results show the linear dependence of [Fe(CN)6]3−/4− redox signal changes on LDL concentration for both biosensors, in the range from 0.01 ng/mL to 1.0 n/mL.
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Comparison of lateral flow immunoassays based on oriented and nonoriented immobilization of antibodies for the detection of aflatoxin B1.
TL;DR: In this paper , a lateral flow immunoassay (LFIA) was used for the detection of aflatoxin B1 (AFB1) in maize and peanut extracts and the results showed that the LFIA method established by the oriented immobilization strategy reduced the sensitivity of AFB1 detection.
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Design and Analysis of Highly Sensitive LSPR-Based Metal–Insulator–Metal Nano-Discs as a Biosensor for Fast Detection of SARS-CoV-2
A. Taghipour,Hamid Heidarzadeh +1 more
TL;DR: In this paper , a 3D FDTD simulation of Au/SiO2/Au metal-insulator-metal (MIM) nanostructures as a biosensor was performed.
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Simple diagnosis of cancer by detecting CEA and CYFRA 21-1 in saliva using electronic sensors
Sowmya Joshi,Shashidhar Kallappa,Pranjal Singh Rajput Yogesh Kumar,Sudhanshu Shukla,Ruma Ghosh +4 more
TL;DR: In this paper , the authors report the development of portable and rapid electronic biosensors for quantitative detection of two secretive cancer biomarkers-Carcinoembryonic antigen (CEA) and Cytokeratin fragment 19 (CYFRA 21-1).
References
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PDB2PQR: an automated pipeline for the setup of Poisson–Boltzmann electrostatics calculations
TL;DR: The PDB2PQR web service is intended to facilitate the setup and execution of Electrostatics calculations for both experts and non-experts and thereby broaden the accessibility to the biological community of continuum electrostatics analyses of biomolecular systems.
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Mesoporous Silica Nanoparticles: Synthesis, Biocompatibility and Drug Delivery
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IgG subclasses and allotypes: from structure to effector functions.
TL;DR: IgG-polymorphisms and post-translational modification of the antibodies in the form of glycosylation, affect IgG-function will be the focus of the current review.
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Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin
Bijan Zakeri,Jacob O. Fierer,Emrah Celik,Emily Chittock,Ulrich Schwarz-Linek,Vincent T. Moy,Mark Howarth +6 more
TL;DR: The robust reaction conditions and irreversible linkage of SpyTag shed light on spontaneous isopeptide bond formation and should provide a targetable lock in cells and a stable module for new protein architectures.