ortho-C–H Oxygenation of Weakly Coordinating Amides and Ketones by Rhoda-Electrocatalysis
About: This article is published in Synfacts.The article was published on 2021-05-01. It has received None citations till now.
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TL;DR: In this article, a bimetallic rhodium catalysis manifold was shown to activate C-H oxygenation by weakly O-coordinating amides and ketones, and diverse dihydrooxazinones were selectively accessed by the judicious choice of current.
Abstract: Rhodium-electrocatalyzed arene C-H oxygenation by weakly O- coordinating amides and ketones have been established by bimetallic electrocatalysis. Likewise, diverse dihydrooxazinones were selectively accessed by the judicious choice of current, enabling twofold C-H functionalization. Detailed mechanistic studies by experiment, mass spectroscopy and cyclovoltammetric analysis provided support for an unprecedented electrooxidation-induced C-H activation by a bimetallic rhodium catalysis manifold.
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