Outcomes after adrenalectomy for unilateral primary aldosteronism: an international consensus on outcome measures and analysis of remission rates in an international cohort
Tracy Ann Williams,Tracy Ann Williams,Jacques W.M. Lenders,Jacques W.M. Lenders,Paolo Mulatero,Jacopo Burrello,Marietta Rottenkolber,Christian Adolf,Fumitoshi Satoh,Laurence Amar,Marcus Quinkler,Jaap Deinum,Felix Beuschlein,Kanako Kiriyama Kitamoto,Uyen Thi Phuong Pham,Ryo Morimoto,Hironobu Umakoshi,Aleksander Prejbisz,Tomaz Kocjan,Mitsuhide Naruse,Michael Stowasser,Tetsuo Nishikawa,William F. Young,Celso E. Gomez-Sanchez,John W. Funder,Martin Reincke +25 more
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TLDR
Consensus was reached for criteria for six outcomes based on blood pressure, use of antihypertensive drugs, plasma potassium and aldosterone concentrations, and plasma renin concentrations or activities based on clinical and biochemical outcomes.About:
This article is published in The Lancet Diabetes & Endocrinology.The article was published on 2017-09-01 and is currently open access. It has received 523 citations till now. The article focuses on the topics: Retrospective cohort study & Cohort study.read more
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Cardiovascular events and target organ damage in primary aldosteronism compared with essential hypertension: a systematic review and meta-analysis
Silvia Monticone,Fabrizio D'Ascenzo,Claudio Moretti,Tracy Ann Williams,Tracy Ann Williams,Franco Veglio,Fiorenzo Gaita,Paolo Mulatero +7 more
TL;DR: The association between primary aldosteronism and adverse cardiac and cerebrovascular events, target organ damage, diabetes, and metabolic syndrome, compared with the association of essential hypertension was assessed.
Journal ArticleDOI
Cardiometabolic outcomes and mortality in medically treated primary aldosteronism: a retrospective cohort study
TL;DR: The current practice of MR antagonist therapy in primary aldosteronism is associated with significantly higher risk for incident cardiometabolic events and death, independent of blood pressure control, than for patients with essential hypertension.
Journal ArticleDOI
Diagnosis and treatment of primary aldosteronism: practical clinical perspectives.
TL;DR: Clinicians should perform case detection testing for primary aldosteronism at least once in all patients with hypertension to determine whether patients with confirmed PA have a disease that can be cured with surgery or whether it should be treated medically.
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The Expanding Spectrum of Primary Aldosteronism: Implications for Diagnosis, Pathogenesis, and Treatment.
TL;DR: Evidence suggesting that primary aldosteronism manifests across a wide spectrum of severity, ranging from mild to overt, that correlates with cardiovascular risk is reviewed, as well as emerging evidence from genetic studies that begin to provide a theoretical explanation for the pathogenesis.
Journal ArticleDOI
Adrenalectomy Lowers Incident Atrial Fibrillation in Primary Aldosteronism Patients at Long Term.
Gian Paolo Rossi,Giuseppe Maiolino,Alberto Flego,Anna Belfiore,Giampaolo Bernini,B. Fabris,Claudio Ferri,Gilberta Giacchetti,Claudio Letizia,Mauro Maccario,Francesca Mallamaci,Maria Lorenza Muiesan,Massimo Mannelli,Aurelio Negro,Gaetana Palumbo,Gabriele Parenti,Ermanno Rossi,Franco Mantero +17 more
TL;DR: By showing that during a long-term follow-up adrenalectomized aldosterone-producing adenoma patients have a similar long- term outcome of optimally treated PH patients, whereas, at variance, medically treated PA patients remain at a higher risk of atrial fibrillation, this large prospective study emphasizes the importance of an early identification of PA patients who need adrenalectomy as a key measure to prevent incident atrialfibrillation
References
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2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).
Giuseppe Mancia,Robert Fagard,Krzysztof Narkiewicz,Josep Redon,Alberto Zanchetti,Michael Böhm,Thierry Christiaens,Renata Cifkova,Guy De Backer,Anna F. Dominiczak,Maurizio Galderisi,Diederick E. Grobbee,Tiny Jaarsma,Paulus Kirchhof,Sverre E. Kjeldsen,Stéphane Laurent,Athanasios J. Manolis,Peter M. Nilsson,Luis M. Ruilope,Roland E. Schmieder,Per Anton Sirnes,Peter Sleight,Margus Viigimaa,Bernard Waeber,Faiez Zannad,Michel Burnier,Ettore Ambrosioni,Mark Caufield,Antonio Coca,Michael H. Olsen,Costas Tsioufis,Philippe van de Borne,José Luis Zamorano,Stephan Achenbach,Helmut Baumgartner,Jeroen J. Bax,Héctor Bueno,Veronica Dean,Christi Deaton,Çetin Erol,Roberto Ferrari,David Hasdai,Arno W. Hoes,Juhani Knuuti,Philippe Kolh,Patrizio Lancellotti,Aleš Linhart,Petros Nihoyannopoulos,Massimo F Piepoli,Piotr Ponikowski,Juan Tamargo,Michal Tendera,Adam Torbicki,William Wijns,Stephan Windecker,Denis Clement,Thierry C. Gillebert,Enrico Agabiti Rosei,Stefan D. Anker,Johann Bauersachs,Jana Brguljan Hitij,Mark J. Caulfield,Marc De Buyzere,Sabina De Geest,Geneviève Derumeaux,Serap Erdine,Csaba Farsang,Christian Funck-Brentano,Vjekoslav Gerc,Giuseppe Germanò,Stephan Gielen,Herman Haller,Jens Jordan,Thomas Kahan,Michel Komajda,Dragan Lovic,Heiko Mahrholdt,Jan Östergren,Gianfranco Parati,Joep Perk,Jorge Polónia,Bogdan A. Popescu,Zeljko Reiner,Lars Rydén,Yuriy Sirenko,Alice Stanton,Harry A.J. Struijker-Boudier,Charalambos Vlachopoulos,Massimo Volpe,David A. Wood +89 more
TL;DR: In this article, a randomized controlled trial of Aliskiren in the Prevention of Major Cardiovascular Events in Elderly people was presented. But the authors did not discuss the effect of the combination therapy in patients living with systolic hypertension.
Journal ArticleDOI
2013 ESH/ESC Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)
Giuseppe Mancia,Robert Fagard,Krzysztof Narkiewicz,Josep Redon,Alberto Zanchetti,Michael Böhm,Thierry Christiaens,Renata Cifkova,Guy De Backer,Anna Dominiczak,Maurizio Galderisi,Diederick E. Grobbee,Tiny Jaarsma,Paulus Kirchhof,Sverre E. Kjeldsen,Stephane Laurent,Athanasios J. Manolis,Peter M. Nilsson,Luis M. Ruilope,Roland E. Schmieder,Per Anton Sirnes,Peter Sleight,Margus Viigimaa,Bernard Waeber,Faiez Zannad +24 more
TL;DR: 2007 Guidelines for the Management of Arterial Hypertension : The Task Force for the management of Arterspertension of the European Society ofhypertension (ESH) and of theEuropean Society of Cardiology (ESC).
Journal ArticleDOI
The Delphi Technique: Making Sense of Consensus
Chia-Chien Hsu,Brian A. Sandford +1 more
TL;DR: The Delphi technique is well suited as a method for consensus-building by using a series of questionnaires delivered using multiple iterations to collect data from a panel of selected subjects.
Journal ArticleDOI
Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis
Dena Ettehad,Connor A. Emdin,Amit Kiran,Simon G Anderson,Simon G Anderson,Thomas Callender,Thomas Callender,Jonathan Emberson,John Chalmers,Anthony Rodgers,Kazem Rahimi +10 more
TL;DR: In this article, a systematic review and meta-analysis of large-scale blood pressure lowering trials, published between Jan 1, 1966, and July 7, 2015, was performed.
Journal ArticleDOI
The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline
John W. Funder,Robert M. Carey,Franco Mantero,M. Hassan Murad,Martin Reincke,Hirotaka Shibata,Michael Stowasser,William F. Young +7 more
TL;DR: This guideline recommends that all patients with primary aldosteronism undergo adrenal computed tomography as the initial study in subtype testing and to exclude adrenocortical carcinoma and advises that an experienced radiologist should establish/exclude unilateral primary aldehydes using bilateral adrenal venous sampling.
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Prevalence and Clinical Manifestations of Primary Aldosteronism Encountered in Primary Care Practice
A Prospective Study of the Prevalence of Primary Aldosteronism in 1,125 Hypertensive Patients
Gian Paolo Rossi,Giampaolo Bernini,C. Caliumi,Giovambattista Desideri,Bruno Fabris,Claudio Ferri,Chiara Ganzaroli,Gilberta Giacchetti,Claudio Letizia,Mauro Maccario,Francesca Mallamaci,Massimo Mannelli,Mee-Jung Mattarello,A. Moretti,Gaetana Palumbo,Gabriele Parenti,Enzo Porteri,Andrea Semplicini,Damiano Rizzoni,Ermanno Rossi,Marco Boscaro,Achille C. Pessina,Franco Mantero,Papy Study Investigators +23 more