Overview of the European and North American studies on HPV testing in primary cervical cancer screening.
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"Overview of the European and North ..." refers background in this paper
...Interest in the use of HPV testing as a screening test is based on the finding that HPV DNA is present in almost all cervical cancers,[ 4 ] and the availability of easily performed tests, which have demonstrated higher sensitivity for high grade CIN (CIN2+) than that achieved by cytology in several studies....
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"Overview of the European and North ..." refers background in this paper
...Many of these are also likely to be transient, or at least nonprogressive,[ 15 ] and further molecular characterization of these lesions may help to clarify which have progressive potential....
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692 citations
"Overview of the European and North ..." refers background in this paper
...It is generally believed that only persistent HPV infections are associated with pre-cancerous lesions.[11][ 16 ][17][18] Currently, persistence of HPV can be determined only by repeated tests 6-12 months apart....
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"Overview of the European and North ..." refers background or methods or result in this paper
...It is generally believed that only persistent HPV infections are associated with pre-cancerous lesions.[ 11 ][16][17][18] Currently, persistence of HPV can be determined only by repeated tests 6-12 months apart....
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...In the HART study,[ 11 ] women who were cytology negative and HPV positive, or whose cytology showed borderline changes (regardless of HPV status), were randomised to either immediate colposcopy or 6 monthly surveillance with HPV and cytology (with an exit colposcopy at 1 year)....
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...The studies included have published their initial results comparing HPV testing to cytology in routine screening.[5][6][7][8][9][10][ 11 ][12] However, these results have been reported in different ways, and here we provide a unified analysis including a comparison against cytology, both overall and for different age groups....
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