Oxidative stress and reactive nitrogen species generation during renal ischemia.
Citations
367 citations
Cites background from "Oxidative stress and reactive nitro..."
...Moreover, when tissues are exposed to ischemia followed by reperfusion (I/R), ROS are extensively generated in the early stage of reperfusion to cause serious damage to tissues in various organs, including the liver [1], brain [2], heart [3], and kidney [4]....
[...]
353 citations
Cites background from "Oxidative stress and reactive nitro..."
..., 1998), amyotrophic lateral sclerosis (ALS) (Cookson and Shaw, 1999), and ischemia–reperfusion (Hall et al., 1995a,b, 2004; Walker et al., 2001; Zou and Bachschmid, 1999)....
[...]
...…AD (Smith et al., 1997, Tohgi et al., 1999; Castegna et al., 2003; Hensley et al., 1998), Parkinson’s disease (PD) (Good et al., 1998), amyotrophic lateral sclerosis (ALS) (Cookson and Shaw, 1999), and ischemia–reperfusion (Hall et al., 1995a,b, 2004; Walker et al., 2001; Zou and Bachschmid, 1999)....
[...]
174 citations
Cites background from "Oxidative stress and reactive nitro..."
...Lipid peroxidation and DNA damage in ischemia are associated with the formation of 3-nitrotyrosine, a biomarker for ROS/RNS, suggesting that NO•, O2•−, and/or peroxynitrite, contribute to renal oxidative damage [18,19]....
[...]
...An imbalance in NO• and O2 production during hypoxia and I/R injury may contribute to renal cell damage [18,19]....
[...]
...Lipid peroxidation and DNA damage in ischemia are associated with the formation of 3-nitrotyrosine, a biomarker for ROS/R S, suggesting that NO•, O2, and/or peroxynitrite, contribute to renal oxidative damage [18,19]....
[...]
165 citations
164 citations
References
6,456 citations
2,713 citations
2,113 citations
"Oxidative stress and reactive nitro..." refers background in this paper
...The reaction is extremely fast and will occur at a near diffusion-limited rate (Huie and Padmaja, 1993)....
[...]
1,526 citations
"Oxidative stress and reactive nitro..." refers background in this paper
...ONOO– is a potent and versatile oxidant that can react with cellular lipids, proteins, and DNA (Pryor and Squadrito, 1995)....
[...]
...ONOO is a potent and versatile oxidant that can react with cellular lipids, proteins, and DNA (Pryor and Squadrito, 1995)....
[...]
978 citations
"Oxidative stress and reactive nitro..." refers background in this paper
...Despite the fact that numerous antioxidants afford some degree of protection against renal I-R injury (De Vecchi et al., 1998; Paller and Hedlund, 1988; Paller et al., 1984), the role of oxidants in the development of acute renal failure due to I-R remains controversial because direct evidence of hydroxyl radial formation is lacking (Zager et al....
[...]