Pain affect encoded in human anterior cingulate but not somatosensory cortex.
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...; similarly, the unpleasantness of thermal pain has been directly correlated with ACC activation using hypnotic manipulatio...
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Cites background from "Pain affect encoded in human anteri..."
...studied changes in neural activity associated with the analgesic effects of hypnosis in different segments of the AC...
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...Distraction from pain signals in experimental pain has been shown in other experiments to decrease activation of PAG and decrease pain perception.(164,165) Also, opiates excite off cells and inhibit on cells....
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...Studies have shown that the activity of the anterior cingulate gyrus increases with peripheral pain stimuli, such as heat applied to the skin, but it also has increased activity when warm stimuli are applied if the patient is expecting hot stimuli.(158,164,165) Negative anticipation causes key brain areas to activate, and the subject then appears to focus, attend to, and rate the pain stimuli as more severe....
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References
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