Paracentral acute middle maculopathy and acute macular neuroretinopathy following SARS-CoV-2 infection.
Jonathan Virgo,Moin Mohamed +1 more
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TLDR
COVID-19 has been reported in association with acute limb ischaemia, stroke and the so called “paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 infection” and PAMM and AMN have similar underlying pathophysiology.Abstract:
This report cases of two patients who presented with a new paracentral scotoma following SARS-CoV-2 infection. Patient 1 is a 37-year-old Caucasian female in week 14 of an uncomplicated pregnancy presented with a 1-day history of abrupt onset, faintly colourful, left eye paracentral scotoma. This was 35 days following the onset of a febrile illness with cough and anosmia. SARS-CoV-2 nasopharyngeal swab was not performed during the infection, but subsequently positive serology (IgG) has been confirmed. Past medical history included acephalgic visual migraine aura and right toxoplasma chorioretinitis. Examination showed normal visual acuity, no uveitis and fundoscopy was normal in the left eye. OCT changes correlated with the location of the scotoma. A focal area of hyper-reflective change in the inner and outer plexiform layers with inner nuclear layer volume loss was seen consistent with paracentral acute middle maculopathy (PAMM). Bloods were normal, including ESR, CRP, lipids, glucose, ANA and anti-phospholipid antibodies. An electrocardiogram and carotid Doppler ultrasound were normal. Patient 2 is a 32-year-old Caucasian male presented with a 4-day history of abrupt onset, faintly colourful, right eye paracentral scotoma. This was 16 days following the onset of nasopharyngeal swab confirmed COVID-19. Past medical history included acephalgic visual migraine aura. Examination showed normal visual acuity, no uveitis and fundoscopy was normal. Changes on infrared reflectance (white arrow) and OCT correlated with the location of the scotomaA focal area of faint outer plexiform layer hyper-reflective change and disruption of the interdigitation zone were seen consistent with acute macular neuroretinopathy. These patients developed PAMM and AMN soon after confirmed SARS-CoV-2 infection and possibly represent postinfectious complications.read more
Citations
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COVID-19 and Eye: A Review of Ophthalmic Manifestations of COVID-19.
TL;DR: A literature search was performed for the publications on ophthalmic manifestations of coronavirus disease-19 (COVID-19) between January 1, 2020 and January 31, 2021 as mentioned in this paper.
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Association of Ocular Adverse Events With Inactivated COVID-19 Vaccination in Patients in Abu Dhabi.
Francesco Pichi,Francesco Pichi,shaikha aljneibi,Piergiorgio Neri,Piergiorgio Neri,Steven Hay,Christine Dackiw,Nicola G. Ghazi +7 more
TL;DR: In a case series study of 7 patients, the timing of transient and ocular complications 5.2 days after vaccination with an inactivated COVID-19 vaccine supported an association with the ocular findings, but a causal relationship cannot be established from this study design as discussed by the authors.
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Pierre Gascon,Antoine Briantais,Emmanuelle Bertrand,Prithvi Ramtohul,Alban Comet,Marie Beylerian,Lauren Sauvan,L Swiader,Jean Marc Durand,Danièle Denis +9 more
TL;DR: A 53-year-old man presented with acute loss of vision, negative scotoma and dyschromatopsia in his left eye and SARSCov-2 was confirmed by chest computed tomography-scan and RT-PCR in this patient.
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Central retinal vein occlusion in a young healthy COVID-19 patient: A case report.
TL;DR: A unique case of a healthy 33-year-old suspected COVID-19 patient who presented with unilateral Central Retinal Vein Occlusion, possibly as a complication of CO VID-19 is detailed, emphasizing the need for further investigation of ocular complication associated with this novel disease.
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Impending Central Retinal Vein Occlusion in a Patient with Coronavirus Disease 2019 (COVID-19).
Alessandro Invernizzi,Alessandro Invernizzi,Marco Pellegrini,Dario Messenio,Matteo Giuseppe Cereda,Pietro Olivieri,Anna Maria Brambilla,Giovanni Staurenghi +7 more
TL;DR: Retinal circulation should be considered as a potential site for thromboembolic complications from COVID-19.
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