Passiflora: a review update.

doi:10.1016/J.JEP.2004.02.023

Home
/
Papers
/
Passiflora: a review update.

Journal Article•DOI•

Passiflora: a review update.

Kamaldeep Dhawan¹, Sanju Dhawan², Anupam Sharma²•Institutions (2)

Government of Haryana¹, Panjab University, Chandigarh²

01 Sep 2004-Journal of Ethnopharmacology (Elsevier)-Vol. 94, Iss: 1, pp 1-23

TL;DR: Various virgin areas of research on the species of this genus have been highlighted with a view to explore, isolate and identify the medicinally important phyto-constituents which could be utilized to alleviate various diseases affecting the mankind.

read less

About: This article is published in Journal of Ethnopharmacology.The article was published on 2004-09-01. It has received 519 citations till now. The article focuses on the topics: Passiflora incarnata & Passiflora alata.

...read moreread less

Citations

PDF

Open Access

More filters

Journal Article•DOI•

Herbal extracts and phytochemicals: plant secondary metabolites and the enhancement of human brain function.

[...]

David O. Kennedy¹, Emma L. Wightman¹•Institutions (1)

Northumbria University¹

01 Jan 2011-Advances in Nutrition

TL;DR: This review assesses the current evidence for the efficacy of a range of readily available plant-based extracts and chemicals that may improve brain function and which have attracted sufficient research in this regard to reach a conclusion as to their potential effectiveness as nootropics.

...read moreread less

563 citations

Journal Article•DOI•

Ethnomedicines used in Trinidad and Tobago for urinary problems and diabetes mellitus

[...]

Cheryl Lans¹•Institutions (1)

University of Victoria¹

13 Oct 2006-Journal of Ethnobiology and Ethnomedicine

TL;DR: Chamaesyce hirta, Cissus verticillata, Kalanchoe pinnata, Peperomia spp.

...read moreread less

Abstract: This paper is based on ethnobotanical interviews conducted from 1996–2000 in Trinidad and Tobago with thirty male and female respondents. A non-experimental validation was conducted on the plants used for urinary problems and diabetes mellitus: This is a preliminary step to establish that the plants used are safe or effective, to help direct clinical trials, and to inform Caribbean physicians of the plants' known properties to avoid counter-prescribing. The following plants are used to treat diabetes: Antigonon leptopus, Bidens alba, Bidens pilosa, Bixa orellana, Bontia daphnoides, Carica papaya, Catharanthus roseus, Cocos nucifera, Gomphrena globosa, Laportea aestuans, Momordica charantia, Morus alba, Phyllanthus urinaria and Spiranthes acaulis. Apium graviolens is used as a heart tonic and for low blood pressure. Bixa orellana, Bontia daphnoides, Cuscuta americana and Gomphrena globosa are used for jaundice. The following plants are used for hypertension: Aloe vera, Annona muricata, Artocarpus altilis, Bixa orellana, Bidens alba, Bidens pilosa, Bonta daphnoides, Carica papaya, Cecropia peltata, Citrus paradisi, Cola nitida, Crescentia cujete, Gomphrena globosa, Hibiscus sabdariffa, Kalanchoe pinnata, Morus alba, Nopalea cochinellifera, Ocimum campechianum, Passiflora quadrangularis, Persea americana and Tamarindus indicus. The plants used for kidney problems are Theobroma cacao, Chamaesyce hirta, Flemingia strobilifera, Peperomia rotundifolia, Petiveria alliacea, Nopalea cochinellifera, Apium graveolens, Cynodon dactylon, Eleusine indica, Gomphrena globosa, Pityrogramma calomelanos and Vetiveria zizanioides. Plants are also used for gall stones and for cooling. Chamaesyce hirta, Cissus verticillata, Kalanchoe pinnata, Peperomia spp., Portulaca oleraceae, Scoparia dulcis, and Zea mays have sufficient evidence to support their traditional use for urinary problems, "cooling" and high cholesterol. Eggplant extract as a hypocholesterolemic agent has some support but needs more study. The plants used for hypertension, jaundice and diabetes that may be safe and justify more formal evaluation are Annona squamosa, Aloe vera, Apium graveolens, Bidens alba, Carica papaya, Catharanthus roseus, Cecropia peltata, Citrus paradisi, Hibsicus sabdariffa, Momordica charantia, Morus alba, Persea americana, Phyllanthus urinaria, Tamarindus indicus and Tournefortia hirsutissima. Several of the plants are used for more than one condition and further trials should take this into account.

...read moreread less

404 citations

Journal Article•DOI•

Beyond THC: The New Generation of Cannabinoid Designer Drugs

[...]

Liana Fattore¹, Liana Fattore², Walter Fratta¹•Institutions (2)

University of Cagliari¹, National Research Council²

21 Sep 2011-Frontiers in Behavioral Neuroscience

TL;DR: An escalating number of compounds with cannabinoid receptor activity are currently being found as ingredients of Spice, of which almost nothing is known in terms of pharmacology, toxicology, and safety.

...read moreread less

Abstract: Synthetic cannabinoids are functionally similar to delta9-tetrahydrocannabinol (THC), the psychoactive principle of cannabis, and bind to the same cannabinoid receptors in the brain and peripheral organs. From 2008, synthetic cannabinoids were detected in herbal smoking mixtures sold on websites and in “head shops” under the brand name of Spice Gold, Yucatan Fire, Aroma, and others. Although these products (also known as “Spice drugs” or “legal highs”) do not contain tobacco or cannabis, when smoked they produce effects similar to THC. Intoxication, withdrawal, psychosis and death have been recently reported after consumption, posing difficult social, political and health challenges. More than 140 different Spice products have been identified to date. The ability to induce strong cannabis-like psychoactive effects, along with the fact that they are readily available on the Internet, still legal in many countries, marketed as natural safe substances, and undetectable by conventional drug screening tests, has rendered these drugs very popular and particularly appealing to young and drug-naive individuals seeking new experiences. An escalating number of compounds with cannabinoid receptor activity are currently being found as ingredients of Spice, of which almost nothing is known in terms of pharmacology, toxicology and safety. Since legislation started to control the synthetic cannabinoids identified in these herbal mixtures, many new analogs have appeared on the market. New cannabimimetic compounds are likely to be synthesized in the near future to replace banned synthetic cannabinoids, leading to a “dog chasing its tail” situation. Spice smokers are exposed to drugs that are extremely variable in composition and potency, and are at risk of serious, if not lethal, outcomes. Social and health professionals should maintain a high degree of alertness for Spice use and its possible psychiatric effects in vulnerable people.

...read moreread less

400 citations

Cites background from "Passiflora: a review update."

...) that is well known to possess anxiolytic properties (Dhawan et al., 2004)....
[...]
...…of THC, JWH-018, and JWH-073 identified among 15 other synthetic cannabinoids, whereas none of the listed ingredients were detectable (Schneir et al., 2011), with the only exception of passion flower (Passiflora sp.) that is well known to possess anxiolytic properties (Dhawan et al., 2004)....
[...]

Journal Article•DOI•

"Spice" girls: synthetic cannabinoid intoxication.

[...]

Aaron B. Schneir¹, Jennifer Cullen¹, Binh T. Ly¹•Institutions (1)

University of California, San Diego¹

01 Mar 2011-Journal of Emergency Medicine

TL;DR: It is suspected that use of "spice" products may increase, and anxiety was a prominent presentation in both of the patients described here, and future studies will describe the manifestations of intoxication and toxicity with the various synthetic cannabinoids.

...read moreread less

Abstract: Background “Spice” refers to various synthetic cannabinoid-containing products that seem to have rapidly become popular recreational drugs of abuse. Very little medical literature currently exists detailing the adverse effects and emergency department (ED) presentations associated with “spice” use. Objectives To describe the presentation of 2 patients who recreationally used a “spice” product and to briefly summarize what is known about “spice” and synthetic cannabinoids. Case Report Two patients presented to the ED with, predominantly, anxiety after recreationally using a “spice” product that we subsequently confirmed to contain the synthetic cannabinoids, JWH-018 and JWH-073. Conclusion We suspect that use of “spice” products may increase. Although anxiety was a prominent presentation in both of the patients described here, undoubtedly, future studies will describe the manifestations of intoxication and toxicity with the various synthetic cannabinoids.

...read moreread less

213 citations

Cites background from "Passiflora: a review update."

...), to have reported psychotropic effects, specifically anxiolytic properties (11)....
[...]

Journal Article•DOI•

Formulation development and systematic optimization of solid lipid nanoparticles of quercetin for improved brain delivery.

[...]

Sanju Dhawan¹, Rishi Kapil¹, Bhupinder Singh¹•Institutions (1)

Panjab University, Chandigarh¹

01 Mar 2011-Journal of Pharmacy and Pharmacology

TL;DR: Solid lipid nanoparticles of quercetin are formulating for intravenous administration in order to improve its permeation across the blood–brain barrier into the CNS, and eventually to improve the therapeutic efficacy of this molecule in Alzheimer's disease.

...read moreread less

Abstract: Objective This study aims at formulating solid lipid nanoparticles (SLNs) of quercetin, a natural flavonoid with established antioxidant activity, for intravenous administration in order to improve its permeation across the blood–brain barrier into the CNS, and eventually to improve the therapeutic efficacy of this molecule in Alzheimer's disease. Methods The SLNs of quercetin were formulated using Compritol as the lipid and Tween 80 as the surfactant through a microemulsification technique, and optimized employing a 32 central composite design (CCD). Selection of the optimized SLN formulation, using brute-force methodology and overlay plots, was based on its efficiency of entrapping quercetin inside the lipophilic core, particle size, surface charge potential and ability of the SLNs to release the entrapped drug completely. The optimized formulation was subjected to various in-vivo behavioral and biochemical studies in Wistar rats. Key findings The optimized formulation exhibited a particle size of less than 200 nm, 85.73% drug entrapment efficiency and a zeta potential of 21.05 mV. In all the in-vivo behavioral and biochemical experiments, the rats treated with SLN-encapsulated quercetin showed markedly better memory-retention vis-a-vis test and pure quercetin-treated rats. Conclusions The studies demonstrated successful targeting of the potent natural antioxidant, quercetin, to brain as a novel strategy having significant therapeutic potential to treat Alzheimer's disease.

...read moreread less

190 citations

1
2
3
4
…
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104

Collapse

References

PDF

Open Access

More filters

Book•

Indian Medicinal Plants

[...]

Kanhoba Ranchoddas Kirtikar, Baman Das Basu

09 Jan 2018

TL;DR: Indian medicinal plants/, Indian medicinal plants /, مرکز فناوری اطلاعات و اصاع رسانی, کδاوρزی

...read moreread less

Abstract: Indian medicinal plants / , Indian medicinal plants / , مرکز فناوری اطلاعات و اطلاع رسانی کشاورزی

...read moreread less

8,252 citations

Book•

Glossary of Indian Medicinal Plants

[...]

R. N. Chopra, S. L. Nayar, I. C. Chopra

01 Jan 1956

5,524 citations