Figure 5. In vivoMRI of chronic IR injury. (a) Short-axis T1-weightedMR images obtained before and after injection of Gd–DTPA (row 1), micelles (row 2) and liposomes (row 3) at week 1 after IR injury. (b) Group-averaged CNRs between infarct and remote tissue at different time points after injection. * p< 0.05 vs all time points; † p< 0.05 vs 1.4h after injection; and †† p< 0.05 vs all contrast agents at 0.1h after injection. (c) MRI at week 2 after IR injury before and after injection of Gd–DTPA (row 1), micelles (row 2) and liposomes (row 3). (b) Group-averaged contrast-to-noise ratios between infarct and remote tissue at different time points after injection. * p< 0.05 vs all time points and †† p< 0.05 vs all contrast agents at 0.1h after injection.
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