Peptide Synthesis by Asymmetric Transamination of α-Keto Amides
Hisashi Yamamoto,An Wu +1 more
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This article is published in Synfacts.The article was published on 2021-12-01 and is currently open access. It has received 0 citations till now. The article focuses on the topics: Transamination & Peptide synthesis.read more
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Asymmetric biomimetic transamination of α-keto amides to peptides.
Weiqi Cai,Xuelong Qiao,Hao Zhang,Bo Li,Jianhua Guo,Liangliang Zhang,Wen-Wen Chen,Baoguo Zhao +7 more
TL;DR: Based on the concept of multiple imitation of transaminases, this article reported N-quaternized axially chiral pyridoxamines for enantioselective transamination of α-keto amides, to produce various peptides in good yields with excellent enantio- and diastereoselectivities.