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Journal ArticleDOI

Perception and awareness of covid-19 among urban and rural population – a survey

01 Oct 2020-International journal of current research and review (Radiance Research Academy)-Vol. 12, Iss: 19, pp 135-142
TL;DR: According to the study, rural people are less aware of Covid-19 than urban people and rural people need far more knowledge and awareness about COVID-19 for prevention and control of infection.
Abstract: Introduction: SARS-CoV-2 is one of seven types of coronavirus Infections caused by them range from mild to deadly Some complications of COVID-19 can be caused by a condition known as cytokine release syndrome or cytokine storm The patients with COVID-19 should be protected from nosocomial infection in hospitals This study mainly aims to know about the awareness and understanding of rural and urban populations about the COVID-19 virus Materials and Methods: A total of 100 participants were involved in this survey Participants in the study belong to rural (Am-mapettai, Kachirapalayam-Kallakurichi district of Tamil Nadu) and urban (Trichy, Salem, Madurai, and Chennai cities) places of Tamil Nadu, India The questions were simple and understandable and it was distributed through WhatsApp and the Google forms Data was collected from filled questionnaires and analyzed using SPSS software Results: From the 100 responses, 53% of the study population was urban and 47% belong to rural areas 66% of participants accept that urban populations are more prone to the spread of coronavirus infection than the urban population 60% of participants agree that both urban and rural people are aware of coronavirus 65% of participants say that COVID-19 spread occurs due to droplet transmission and touching objects used by infected patients 65% of participants say that mouth mask, handwash, and social isolation protects from the transmission of infection The majority of the urban population responded that the urban areas are more prone to COVID-19 infection than the rural areas However, there was no significant difference between the opinion of urban and rural populations on the infection-prone areas, p-value = 0 687 (>0 05) The majority of the urban population (41%) believes that coronavirus spreads through both the routes (droplets and touching objects used by infected patients) and the rural population responded less (24%) for both the routes of transmission, p-value = 0 016 (<0 05), hence it was statistically significant More of the urban population (27%) believes that the lockdown was very useful in minimizing the coronavirus transmission when compared to the rural population (15%), p-value = 0 004 (<0 05), hence it was statistically significant Conclusion: According to the study, rural people are less aware of Covid-19 than urban people Rural people need far more knowledge and awareness about COVID-19 for prevention and control of infection © IJCRR

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DissertationDOI
01 Jan 1998
TL;DR: This chapter discusses the development of dissertation organization in the context of a post-graduate education and some of the basic principles of such an organization are explained.
Abstract: vii CHAPTER 1. GENERAL INTRODUCTION 1 Dissertation Organization

2 citations

Journal ArticleDOI
10 Oct 2022
TL;DR: In this article , the authors analyzed the differences in perceived susceptibility and perceived severity in the implementation of Covid-19 health protocol in urban and rural communities, and they showed that people with high perceived susceptibility can improve preventive behavior against Covid19.
Abstract: Abstract—Perceived Susceptibility is an individual's subjective perception of the risk of getting a disease, and Perceived Severity is information that a person believes about the severity or seriousness of a disease. A person with high Perceived Susceptibility and Perceived Severity can improve preventive behavior against Covid-19. The purpose of this study was to analyze the differences in Perceived Susceptibility and Perceived Severity in the implementation of the Covid-19 health protocol in urban and rural communities. The research method is quantitative in the form of observational analytic study with cross sectional approach. Data was collected in urban and rural areas with 88 total of respondents. The results of the analysis with the Mann Whitney test show that there is a difference in Perceived Susceptibility based on urban and rural area(p=0.001), education level(p=0.001), occupation(p=0.008), experience of being diagnosed with Covid-19(p=0.025) and there are not any difference based on the source of information(p=0.938). There are differences in Perceived Severity based on urban and rural areas(p=0.026), education level(p=0.005), occupation(p=0.012), experience of being diagnosed with Covid-19 (p= 0.03) and there are not any differences based on the source of information(p=0.877). This study shows that urban communities have higher Perceived Susceptibility and Perceived Severity in the implementation of the Covid-19 health protocol than rural communities. Keywords: covid-19 health protocol, perceived susceptibility, perceived severity Abstrak—Perceived Susceptibility atau persepsi kerentanan merupakan persepsi subyektif seorang individu terhadap risiko terkena suatu penyakit sedangkan Perceived Severity atau persepsi keseriusan merupakan persepsi yang diyakini seseorang tentang suatu keparahan atau keseriusan suatu penyakit. Seseorang dengan Perceived Susceptibility (persepsi kerentanan) dan Perceived Severity (persepsi keseriusan) yang tinggi terhadap Covid-19 dapat meningkatkan perilaku pencegahan terhadap Covid-19. Tujuan penelitian ini adalah menganalisis perbedaan Perceived Susceptibility dan Perceived Severity dalam pelaksanaan protokol kesehatan Covid-19 pada masyarakat perkotaan dan pedesaan. Penelitian menggunakan metode kuantitatif berupa studi analitik observasional dengan pendekatan cross sectional. Pengambilan data dilakukan secara consecutive sampling di dua lokasi yaitu di wilayah perkotaan dan pedesaan dengan total responden sebanyak 88 orang. Hasil analisis dengan Uji Mann Whitney menunjukan adanya perbedaan Perceived Susceptibility berdasarkan wilayah perkotaan dan pedesaan (p=0,001), pendidikan (p=0,001), pekerjaan (p=0,008), pengalaman positif Covid-19 (p=0,025) dan tidak ditemukan adanya perbedaan berdasarkan sumber informasi (p=0,938). Sedangkan untuk Perceived Severity ditemukan adanya perbedaan berdasarkan wilayah perkotaan dan pedesaan (p=0,026), pendidikan (p=0,005), pekerjaan (p=0,012), pengalaman positif Covid-19 (p=0,03) dan tidak ditemukan adanya perbedaan berdasarkan sumber informasi (p=0,877). Penelitian ini menunjukkan masyarakat perkotaan memiliki Perceived Susceptibility dan Perceived Severity yang lebih tinggi dalam menjalankan protokol kesehatan Covid-19 dibanding masyarakat pedesaan. Kata kunci: protokol kesehatan covid-19, perceived susceptibility, perceived severity
References
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Journal ArticleDOI
TL;DR: Human airway epithelial cells were used to isolate a novel coronavirus, named 2019-nCoV, which formed a clade within the subgenus sarbecovirus, Orthocoronavirinae subfamily, which is the seventh member of the family of coronaviruses that infect humans.
Abstract: In December 2019, a cluster of patients with pneumonia of unknown cause was linked to a seafood wholesale market in Wuhan, China. A previously unknown betacoronavirus was discovered through the use of unbiased sequencing in samples from patients with pneumonia. Human airway epithelial cells were used to isolate a novel coronavirus, named 2019-nCoV, which formed a clade within the subgenus sarbecovirus, Orthocoronavirinae subfamily. Different from both MERS-CoV and SARS-CoV, 2019-nCoV is the seventh member of the family of coronaviruses that infect humans. Enhanced surveillance and further investigation are ongoing. (Funded by the National Key Research and Development Program of China and the National Major Project for Control and Prevention of Infectious Disease in China.).

21,455 citations

Journal ArticleDOI
TL;DR: Examining leukocyte and cytokine activity in COVID‐19 focuses on how these levels are altered as the disease progresses and proposed consequences to organ pathology and Viral and host interactions are described to gain further insight into leukocytes biology and how dysregulated cytokine responses lead to disease and/or organ damage.
Abstract: Clinical evidence indicates that the fatal outcome observed with severe acute respiratory syndrome-coronavirus-2 infection often results from alveolar injury that impedes airway capacity and multi-organ failure-both of which are associated with the hyperproduction of cytokines, also known as a cytokine storm or cytokine release syndrome. Clinical reports show that both mild and severe forms of disease result in changes in circulating leukocyte subsets and cytokine secretion, particularly IL-6, IL-1s, IL-10, TNF, GM-CSF, IP-10 (IFN-induced protein 10), IL-17, MCP-3, and IL-1ra. Not surprising, therapies that target the immune response and curtail the cytokine storm in coronavirus 2019 (COVID-19) patients have become a focus of recent clinical trials. Here we review reports on leukocyte and cytokine data associated with COVID-19 disease in 3939 patients in China and describe emerging data on immunopathology. With an emphasis on immune modulation, we also look at ongoing clinical studies aimed at blocking proinflammatory cytokines; transfer of immunosuppressive mesenchymal stem cells; use of convalescent plasma transfusion; as well as immunoregulatory therapy and traditional Chinese medicine regimes. In examining leukocyte and cytokine activity in COVID-19, we focus in particular on how these levels are altered as the disease progresses (neutrophil NETosis, macrophage, T cell response, etc.) and proposed consequences to organ pathology (coagulopathy, etc.). Viral and host interactions are described to gain further insight into leukocyte biology and how dysregulated cytokine responses lead to disease and/or organ damage. By better understanding the mechanisms that drive the intensity of a cytokine storm, we can tailor treatment strategies at specific disease stages and improve our response to this worldwide public health threat.

541 citations

Journal ArticleDOI
12 Jun 2020-PLOS ONE
TL;DR: RT-LAMP specifically detected SARS-CoV-2 in both simulated patient samples and clinical specimens, and could be used for monitoring of exposed individuals or potentially aid with screening efforts in the field and potential ports of entry.
Abstract: Novel Corona virus/Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2 or 2019-nCoV), and the subsequent disease caused by the virus (coronavirus disease 2019 or COVID-19), is an emerging global health concern that requires a rapid diagnostic test. Quantitative reverse transcription PCR (qRT-PCR) is currently the standard for SARS-CoV-2 detection; however, Reverse Transcription Loop-Mediated Isothermal Amplification (RT-LAMP) may allow for faster and cheaper field based testing at point-of-risk. The objective of this study was to develop a rapid screening diagnostic test that could be completed in 30-45 minutes. Simulated patient samples were generated by spiking serum, urine, saliva, oropharyngeal swabs, and nasopharyngeal swabs with a portion of the SARS-CoV-2 nucleic sequence. RNA isolated from nasopharyngeal swabs collected from actual COVID-19 patients was also tested. The samples were tested using RT-LAMP as well as by conventional qRT-PCR. Specificity of the RT-LAMP was evaluated by also testing against other related coronaviruses. RT-LAMP specifically detected SARS-CoV-2 in both simulated patient samples and clinical specimens. This test was performed in 30-45 minutes. This approach could be used for monitoring of exposed individuals or potentially aid with screening efforts in the field and potential ports of entry.

234 citations

Journal ArticleDOI
TL;DR: A debate is taking place on the use of face masks (both cloth and surgical) as a prevention tool in the community vis à vis the recent World Health Organization (WHO) recommendations.
Abstract: Cloth masks are a simple, economic and sustainable alternative to surgical masks as a means of source control of SARS-CoV-2 in the general communityhttps://bit.ly/2x2xTL4

198 citations