Journal Article•
[periodic course of the oxidation of malonic acid in a solution (studies on the kinetics of beolusov's reaction)].
About: This article is published in Biofizika.The article was published on 1964-01-01 and is currently open access. It has received 352 citations till now. The article focuses on the topics: Malonic acid.
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TL;DR: In this article, the authors suggest that shifts in the large-scale environment could alter the prevalence of mixed-phase clouds, potentially affecting surface radiative fluxes and the Arctic energy budget.
Abstract: Mixed-phase clouds, comprising both ice and supercooled liquid water, have a large impact on radiative fluxes in the Arctic. Interactions between numerous local feedbacks sustain these complex cloud systems, leading to the development of a resilient mixed-phase cloud system. The Arctic region is particularly sensitive to climate change. Mixed-phase clouds, comprising both ice and supercooled liquid water, have a large impact on radiative fluxes in the Arctic. These clouds occur frequently during all seasons in the region, where they often persist for many days at a time. This persistence is remarkable given the inherent instability of ice–liquid mixtures. In recent years it has emerged that feedbacks between numerous local processes, including the formation and growth of ice and cloud droplets, radiative cooling, turbulence, entrainment and surface fluxes of heat and moisture, interact to create a resilient mixed-phase cloud system. As well as the persistent mixed-phase cloud state there is another distinct Arctic state, characterized by radiatively clear conditions. The occurrence of either state seems to be related, in part, to large-scale environmental conditions. We suggest that shifts in the large-scale environment could alter the prevalence of mixed-phase clouds, potentially affecting surface radiative fluxes and the Arctic energy budget.
508 citations
TL;DR: Self-organization concepts that were first developed in chemistry and physics and then applied to various morphogenetic problems in biology over the past century are now beginning to be applied to the organization of the living cell.
Abstract: Over the past two decades, molecular and cell biologists have made important progress in characterizing the components and compartments of the cell. New visualization methods have also revealed cellular dynamics. This has raised complex issues about the organization principles that underlie the emergence of coherent dynamical cell shapes and functions. Self-organization concepts that were first developed in chemistry and physics and then applied to various morphogenetic problems in biology over the past century are now beginning to be applied to the organization of the living cell.
465 citations
TL;DR: In this study, design and experimentally demonstrate three transcriptional oscillators in vitro that provide a modular platform for the systematic construction of arbitrary circuits and requires only two essential enzymes to produce and degrade RNA signals.
Abstract: The construction of synthetic biochemical circuits from simple components illuminates how complex behaviors can arise in chemistry and builds a foundation for future biological technologies. A simplified analog of genetic regulatory networks, in vitro transcriptional circuits, provides a modular platform for the systematic construction of arbitrary circuits and requires only two essential enzymes, bacteriophage T7 RNA polymerase and Escherichia coli ribonuclease H, to produce and degrade RNA signals. In this study, we design and experimentally demonstrate three transcriptional oscillators in vitro. First, a negative feedback oscillator comprising two switches, regulated by excitatory and inhibitory RNA signals, showed up to five complete cycles. To demonstrate modularity and to explore the design space further, a positive-feedback loop was added that modulates and extends the oscillatory regime. Finally, a three-switch ring oscillator was constructed and analyzed. Mathematical modeling guided the design process, identified experimental conditions likely to yield oscillations, and explained the system's robust response to interference by short degradation products. Synthetic transcriptional oscillators could prove valuable for systematic exploration of biochemical circuit design principles and for controlling nanoscale devices and orchestrating processes within artificial cells.
308 citations
TL;DR: In this paper, experiments have been carried out on the Belousov-Zhabotinskii reaction in an isothermal continuous stirred tank reactor, where the flow rate was varied from low values where simple single peak oscillations occur to large values where the reactor is in steady state.
Abstract: Experiments have been carried out on the Belousov–Zhabotinskii reaction in an isothermal continuous stirred tank reactor. The flow rate was varied from low values where simple single peak oscillations occur to large values where the reactor is in steady state. Several types of periodic multipeak oscillations were observed. Three regions of nonperiodic behavior were found, each of which occurred in a well defined range of flow rates bracketed by periodic oscillations.
257 citations
TL;DR: In this article, the authors extend the Keldysh technique to enable the computation of out-of-time order correlators such as O(t)O(0,O(t),O(T)O (t) O(0),O (0)
253 citations