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Journal ArticleDOI

Periodontal inflamed surface area: quantifying inflammatory burden

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TLDR
PISA quantifies the inflammatory burden posed by periodontitis and can be easily and broadly applied.
Abstract
Background: Currently, a large variety of classifications is used for periodontitis as a risk factor for other diseases. None of these classifications quantifies the amount of inflamed periodontal tissue, while this information is needed to assess the inflammatory burden posed by periodontitis. Aim: To develop a classification of periodontitis that quantifies the amount of inflamed periodontal tissue, which can be easily and broadly applied. Material and Methods: A literature search was conducted to look for a classification of periodontitis that quantified the amount of inflamed periodontal tissue. A classification that quantified the root surface area affected by attachment loss was found. This classification did not quantify the surface area of inflamed periodontal tissue, however. Therefore, an Excel spreadsheet was developed in which the periodontal inflamed surface area (PISA) is calculated using clinical Attachment Level (CAL), recessions and bleeding on probing (BOP). Results: The PISA reflects the surface area of bleeding pocket epithelium in square millimetres. The surface area of bleeding pocket epithelium quantifies the amount of inflamed periodontal tissue. A freely downloadable spreadsheet is available to calculate the PISA. Conclusion: PISA quantifies the inflammatory burden posed by periodontitis and can be easily and broadly applied.

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Citations
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Journal ArticleDOI

Periodontitis and atherosclerotic cardiovascular disease: consensus report of the Joint EFP/AAP Workshop on Periodontitis and Systemic Diseases.

TL;DR: There is consistent and strong epidemiologic evidence that periodontitis imparts increased risk for future cardiovascular disease; and while in vitro, animal and clinical studies do support the interaction and biological mechanism, intervention trials to date are not adequate to draw further conclusions.
Journal ArticleDOI

Effect of Periodontal Treatment on Glycemic Control of Diabetic Patients A systematic review and meta-analysis

TL;DR: The present meta-analysis suggests that periodontal treatment leads to an improvement of glycemic control in type 2 diabetic patients for at least 3 months.
Journal ArticleDOI

Treatment of periodontitis improves the atherosclerotic profile: a systematic review and meta‐analysis

TL;DR: This systematic review and meta-analyses demonstrate that periodontal treatment improves endothelial function and reduces biomarkers of atherosclerotic disease, especially in those already suffering from CVD and/or diabetes.
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The epidemiological evidence behind the association between periodontitis and incident atherosclerotic cardiovascular disease.

TL;DR: There is evidence for an increased risk of ACVD in patients with PD compared to patients without, however, this may not apply to all groups of the population.
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Periodontitis in established rheumatoid arthritis patients: A cross-sectional clinical, microbiological and serological study

TL;DR: Severity of periodontitis is related to severity of RA, and RA patients with severeperiodontitis have a more robust antibody response against P. gingivalis than non-RA controls, but not all RA patients have cultivable P. rheumatoid arthritis.
References
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Journal ArticleDOI

The prevalence and incidence of coronary heart disease is significantly increased in periodontitis: a meta-analysis.

TL;DR: This meta-analysis indicates that both the prevalence and incidence of CHD are significantly increased in PD, and therefore, PD may be a risk factor for CHD.
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Associations between periodontal disease and risk for atherosclerosis, cardiovascular disease, and stroke. A systematic review.

TL;DR: Most of the literature supports a modest association between periodontal disease and atherosclerosis, but additional large-scale longitudinal epidemiologic and intervention studies are necessary to validate this association and to determine causality.
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Meta-analysis of periodontal disease and risk of coronary heart disease and stroke.

TL;DR: In this paper, the authors analyzed published studies and abstracts in order to provide a quantitative summary of periodontal disease as a risk factor for cardiovascular disease and explore the possible causes for conflicting results in the literature.
Journal ArticleDOI

Associations Between Periodontal Disease and Risk for Nosocomial Bacterial Pneumonia and Chronic Obstructive Pulmonary Disease. A Systematic Review

TL;DR: A meta-analysis was performed on the 5 intervention studies to determine the relationship between oral hygiene intervention and rate of pneumonia in institutionalized patients and the results associating periodontal disease and COPD are preliminary.
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