Journal ArticleDOI
Peripheral arterial vasodilation hypothesis: a proposal for the initiation of renal sodium and water retention in cirrhosis.
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TLDR
The stimulation of the renin‐angiotensin‐aldosterone system, vasopressin release and sympathetic nervous system associated with cirrhosis is not consonant with primary volume expansion, and favors the “overflow” hypothesis.About:
This article is published in Hepatology.The article was published on 1988-09-01. It has received 1475 citations till now. The article focuses on the topics: Effective arterial blood volume & Hepatorenal syndrome.read more
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EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis
Paolo Angeli,Mauro Bernardi,Càndid Villanueva,Claire Francoz,Rajeshwar P. Mookerjee,Jonel Trebicka,Aleksander Krag,Wim Laleman,Pere Ginès +8 more
TL;DR: The panel of experts, having emphasised the importance of initiating aetiologic treatment for any degree of hepatic disease at the earliest possible stage, extended its work to all the complications of cirrhosis which had not been covered by the European Association for the Study of the Liver guidelines.
Journal ArticleDOI
Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis
Vicente Arroyo,Pere Ginès,Alexander L. Gerbes,F J Dudley,Paolo Gentilini,Giacomo Laffi,Telfer B. Reynolds,H. Ring-Larsen,J Schölmerich +8 more
Journal ArticleDOI
EASL clinical practice guidelines on the management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis.
TL;DR: There is a clear rationale for the management of ascites in patients with cirrhosis, as successful treatment may improve outcome and symptoms, and patients with ascites should generally be considered for referral for liver transplantation.
Journal ArticleDOI
Effect of Intravenous Albumin on Renal Impairment and Mortality in Patients with Cirrhosis and Spontaneous Bacterial Peritonitis
Pau Sort,Miquel Navasa,Vicente Arroyo,Xavier Aldeguer,Ramon Planas,Luis Ruiz-del-Arbol,Lluis Castells,Victor Vargas,Germán Soriano,Mónica Guevara,Pere Ginès,Joan Rodés +11 more
TL;DR: In patients with cirrhosis and spontaneous bacterial peritonitis, treatment with intravenous albumin in addition to an antibiotic reduces the incidence of renal impairment and death in comparison with treatment with an antibiotic alone.
Journal ArticleDOI
Incidence, predictive factors, and prognosis of the hepatorenal syndrome in cirrhosis with ascites
Angels Ginès,Angels Escorsell,Pere Ginès,Joan Saló,Wladimiro Jiménez,Luis Inglada,Miquel Navasa,Joan Clària,Antoni Rimola,Vicente Arroyo,Joan Rodés +10 more
TL;DR: The hepatorenal syndrome is a relatively frequent complication in cirrhotic patients with ascites that is associated with an extremely short survival and Liver size, plasma renin activity, and serum sodium concentration are predictors of hepatorenAL syndrome occurrence in these patients.
References
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Journal ArticleDOI
Pathogenesis of sodium and water retention in high-output and low-output cardiac failure, nephrotic syndrome, cirrhosis, and pregnancy (2)
TL;DR: The approach presented in this article should be considered to be a vantage point from which to evaluate states of sodium and water retention, but not to be an exclusive position.
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Prognostic value of arterial pressure, endogenous vasoactive systems, and renal function in cirrhotic patients admitted to the hospital for the treatment of ascites
Josep Llach,Pere Ginès,Vicente Arroyo,Antoni Rimola,Llúcia Titó,Salvatore Badalamenti,Wladimiro Jiménez,Joan Gaya,Francisca Rivera,Joan Rodés +9 more
TL;DR: In patients with cirrhosis and ascites, parameters estimating systemic hemodynamics and renal function are better predictors of survival than those routinely used to estimate hepatic function.
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The treatment of obesity by the "highfat" diet. The inevitability of calories
John Yudkin,Margaret Carey +1 more
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Potential Role of Increased Sympathetic Activity in Impaired Sodium and Water Excretion in Cirrhosis
TL;DR: It is indicated that increased sympathetic activity, as assessed by plasma levels of norepinephrine, correlates closely with sodium and water retention in cirrhotic patients and thus may be of pathogenetic importance.